Recognition Memory in Amnesic Patients: Effect of Temporal Context and Familiarity of Material

Huppert, Felicia A.; Piercy, Malcolm

doi:10.1016/s0010-9452(76)80024-x

Cited by 259 publications

(145 citation statements)

References 12 publications

Supporting

Mentioning

134

Contrasting

Order By: Relevance

“…The selection of memory traces explored by our task appears to be different from the explicit knowledge about the time when a specific piece of information was encountered in relation to other information, a capacity tested with traditional temporal order and recency tasks (Huppert and Piercy, 1976;Hirst and Volpe, 1982;Schacter, 1987;Shimamura et al, 1990;Milner et al, 1991;Shimamura et al, 1991;Parkin and Hunkin, 1993;Kesner et al, 1994;Kopelman et al, 1997b). In such tasks, the test subjects may be presented, for example, with two lists of words some time apart and later be requested to indicate whether a word was presented in the first or second list.…”

Section: Discussionmentioning

confidence: 94%

Selection of Currently Relevant Memories by the Human Posterior Medial Orbitofrontal Cortex

2000

View full text Add to dashboard Cite

We have demonstrated previously that patients producing spontaneous confabulations fail to suppress currently irrelevant memory traces, so that they act and think on the basis of a false, temporally displaced (past) reality. All spontaneous confabulators had anterior limbic damage, in particular of the orbitofrontal cortex and basal forebrain. These findings indicated that these structures are essential for distinguishing between mental representations of ongoing reality and currently irrelevant memories. In the present study, we used a similar experimental paradigm as in our clinical studies and H 2 15O positron emission tomography to explore the selection of currently relevant memories by the healthy human brain. Subjects were repeatedly presented with the same set of pictures, arranged in different order each time, and were requested to indicate picture recurrences within the runs. Thus, performance in the first run depended on new learning, whereas subsequent runs required the distinction between picture repetitions within the current run ("now") and previous picture presentations in earlier runs. Whereas initial learning activated medial temporal structures, subsequent runs provoked circumscribed posterior medial orbitofrontal activation. We suggest that this area is essential for sorting out mental associations that pertain to ongoing reality.

show abstract

Section: Discussionmentioning

confidence: 94%

Selection of Currently Relevant Memories by the Human Posterior Medial Orbitofrontal Cortex

2000

View full text Add to dashboard Cite

show abstract

“…As mentioned in the introduction, amnesic Korsakoff patients have been found to show the low-frequency word advantage in recognition memory tests (e.g., Huppert & Piercy, 1976;Verfaellie et aI., 1991). But how can this be when conscious recollection is the very ability that is assumed to be impaired in the amnesic patients?…”

Section: Discussionmentioning

confidence: 97%

“…Korsakoff patients, like memory-intact subjects, show greater repetition priming effects of low-frequency words than ofhighfrequency words in the lexical decision task (Verfaellie, Cermak, Letourneau, & Zuffante, 1991). In recognition memory tests, Korsakoff patients have shown better performance with low-frequency words than with highfrequency words (Huppert & Piercy, 1976;Verfaellie et al, 1991). Because amnesic subjects perform poorly on tests that require conscious recollection, taken together it seems most parsimonious to interpret these findings in terms of a common perceptual fluency component intact in amnesic subjects that underlies both repetition priming and feelings of familiarity.…”

Section: Macquarie University Sydney New South Wales Australiamentioning

confidence: 98%

“…4. It is also relevant to note that the amnesic subjects who showed superior recognition memory for low-frequency than for high-frequency words were all Korsakoffpatients (Huppert & Piercy, 1976;Verfaellie et aI., 1991), who typically have some frontal lobe damage and are often found to be impaired especially on conceptual processing ability (see, e.g., Cermak, Butters, & Moreines, 1974). It is possible, therefore, that these patients have a particular propensity to rely on perceptual fluency in making recognition memory judgments, which may not be the case with amnesics with different etiologies (see Haist, Shimamura, & Squire, 1992, for a related view).…”

Section: Notesmentioning

confidence: 99%

See 1 more Smart Citation

The word frequency effect in recognition memory versus repetition priming

Kinoshita

1995

Memory & Cognition

View full text Add to dashboard Cite

“…Previous research indicates that amnesic patients also have difficulty in processing temporal order information (Hirst & Volpe, 1982;Huppert & Piercey, 1976;Squire, Nadel, & Slater, 1981). Only one study, Sagar, Gabrieli, Sullivan, and Corkin (1990), found no deficit for patient H.M., who had a bilateral temporal lobectomy.…”

Section: Memory For Temporal Order-humansmentioning

confidence: 99%

Neural mediation of memory for time: Role of the hippocampus and medial prefrontal cortex

Kesner

1998

Psychonomic Bulletin & Review

View full text Add to dashboard Cite

Within the context of the neurobiology of attribute model, memory for the temporal attribute is composed of at least three features-memory for duration, memory for succession, or temporal order, and memory for past and future time perspective within a dual-based (data and knowledge) memory system. Research aimed at testing the assumption that the hippocampus and interconnected neural circuits mediate the temporal attribute within the data-based memory system and the prefrontal cortex and interconnected neural circuits mediate the temporal attribute within the knowledge-based memory system in animals and humans is reviewed. The research indicates that (1) memory for the duration feature of the temporal attribute is mediated by the hippocampus, but not prefrontal cortex, in both animals and humans, (2) memory for the temporal order feature of the temporal attribute based on new information is subserved by both the hippocampus and the prefrontal cortex, but that based on prior knowledge or the ability to use prior knowledge is supported only by prefrontal cortex, and not the hippocampus, in both animals and humans, and (3) memory for the past (time perspective) feature of the temporal attribute is mediated by the hippocampus, whereas memory for the future (time perspective) feature of the temporal attribute is supported by the prefrontal cortex in both animals and humans. There is a clear parallel between animals and humans in terms of hippocampal and prefrontal cortex mediation of the temporal attribute, supporting the assumption of evolutionary continuity. There is support for a greater involvement of the hippocampus in comparison with the prefrontal cortex in mediating temporal attribute information within the data-based memory system. Conversely, there is support for a greater involvement of the prefrontal cortex in comparison with the hippocampus in mediating temporal attribute information within the knowledge-based memory system. Future research needs to concentrate on the development of new paradigms to measure memory for different temporal features and to uncover the critical neural circuits that subserve these temporal features,The structure and utilization of memory is central to one's knowledge of the past, interpretation of the present, and prediction of the future. Therefore, understanding the structural and process components of memory systems at the psychological and neurobiological levels is of paramount importance. In recent years, there have been a number of attempts to divide learning and memory into multiple memory systems. Schacter and Tulving (1994) have suggested that one needs to define memory systems in terms of the kind of information to be represented, the processes associated with the operation of each system, and the neurobiological substrates, including neural structures and mechanisms that subserve each system. Furthermore, it is likely that within each system there are multiple forms or subsystems associated with each memory system, and there are likely to be multiple processes that ...

show abstract

Recognition Memory in Amnesic Patients: Effect of Temporal Context and Familiarity of Material

Cited by 259 publications

References 12 publications

Selection of Currently Relevant Memories by the Human Posterior Medial Orbitofrontal Cortex

Selection of Currently Relevant Memories by the Human Posterior Medial Orbitofrontal Cortex

The word frequency effect in recognition memory versus repetition priming

Neural mediation of memory for time: Role of the hippocampus and medial prefrontal cortex

Contact Info

Product

Resources

About