“…Indeed, the diagnostic complications due to cancer are likely more pronounced than in many common or life-threatening illnesses given the toxicity of treatments, the frequent stigma associated with cancer (e.g., for potentially avoidable cancers such as lung or skin cancer), and the frequent fear of pain, disfigurement or even death (e.g., Gonzalez & Jacobsen, 2012; Lebel & Devens, 2008; Passik, Kirsch, Rosenfeld, McDonald, & Theobald, 2001). The primary source of this difficulty lies in the overlap between the diagnostic criteria for depression (Table 1), as detailed in the Diagnostic and Statistical Manual for Mental Disorders (DSM; American Psychiatric Association, 2013), and the symptoms often attributable to cancer and/or the side effects of treatment (Guo et al, 2006; Kathol, Mutgi, Williams, Clamon, & Noyes, 1990; Passik & Lowery, 2011). The same symptoms may arise from depression, from the cancer itself, from treatment side effects, or from some combination of the three (Koenig, George, Peterson, & Pieper, 1997; McDaniel, Musselman, Porter, Reed, & Nemeroff, 1995).…”