2016
DOI: 10.3389/fphys.2016.00389
|View full text |Cite
|
Sign up to set email alerts
|

Recognition of Fibrotic Infarct Density by the Pattern of Local Systolic-Diastolic Myocardial Electrical Impedance

Abstract: Myocardial electrical impedance is a biophysical property of the heart that is influenced by the intrinsic structural characteristics of the tissue. Therefore, the structural derangements elicited in a chronic myocardial infarction should cause specific changes in the local systolic-diastolic myocardial impedance, but this is not known. This study aimed to characterize the local changes of systolic-diastolic myocardial impedance in a healed myocardial infarction model. Six pigs were successfully submitted to 1… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
19
0

Year Published

2018
2018
2023
2023

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 15 publications
(20 citation statements)
references
References 23 publications
0
19
0
Order By: Relevance
“…The first intervention aimed to induce acute myocardial infarction by occluding the left anterior descending coronary artery during 150 minutes with a catheter balloon, followed by reperfusion, as previously described. 10 Animals were premedicated with midazolam 0.6 mg/kg and ketamine 12 mg/ kg, and then they were submitted to general anesthesia with propofol 2-4 mg/kg and maintained with sevoflurane inhalation (2.5%-3.5%). Fentanyl (5 mg/kg) was administered for analgesia.…”
Section: Study Populationmentioning
confidence: 99%
See 2 more Smart Citations
“…The first intervention aimed to induce acute myocardial infarction by occluding the left anterior descending coronary artery during 150 minutes with a catheter balloon, followed by reperfusion, as previously described. 10 Animals were premedicated with midazolam 0.6 mg/kg and ketamine 12 mg/ kg, and then they were submitted to general anesthesia with propofol 2-4 mg/kg and maintained with sevoflurane inhalation (2.5%-3.5%). Fentanyl (5 mg/kg) was administered for analgesia.…”
Section: Study Populationmentioning
confidence: 99%
“…Although we analyzed the entire impedance spectra in all sites, we preferentially reported the data at 1, 41, 307, and 1000 kHz because we previously verified that these frequencies were highly discriminative. 10,13 To characterize the curve of phasic impedance changes elicited during the cardiac cycle, we measured the amplitude of the curve and the time interval elapsed from the peak of the electrocardiographic R wave to the moment of maximum impedance magnitude (R wave impedance peak time).…”
Section: Myocardial Electrical Impedancementioning
confidence: 99%
See 1 more Smart Citation
“…Unfortunately, the equipment presented by Jorge et al is not suitable to use on human subjects. The same instrumentation was used by Amorós-Figueras et al in the work presented in Recognition of Fibrotic Infarct Density by the Pattern of Local Systolic-Diastolic Myocardial Electrical Impedance [32]. This work demonstrates that there are changes in the myocardial tissue after an infarct, and they suggest that it can be used in ablation procedures via a catheter to detect scar tissue.…”
Section: Invasive Tissue Measurementsmentioning
confidence: 73%
“…Preliminary studies conclude that there is a correlation between the measured resistance and the morphology of the tissue next to the electrode [8]. Amorós-Figueras et al [9] show that in situ impedance measurements in myocardium or epicardium allowed discriminating healthy and infarcted tissue. These results suggest that the tissue remodeling occurring in fibrosis has an EIS signature.…”
Section: Introductionmentioning
confidence: 99%