2023
DOI: 10.18705/2782-3806-2022-2-6-64-77
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Recombinant vaccine candidates with integrated adjuvants provide stimulation of an effective immune response against bacterial infections

Abstract: The use of recombinant proteins as vaccine preparations is limited by their weak immunogenicity, which can be enhanced by the use of adjuvants, the development of which is an important and urgent problem of modern vaccinology. Significantly, adjuvants as additives to vaccine preparations are of concern to clinicians. From this point of view, the idea of including an internal adjuvant into the structure of a recombinant protein molecule is of undoubted interest. Previously, we synthesized and studied two recomb… Show more

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