Recomendaciones GESIDA/SEFH/PNS para mejorar la adherencia al tratamiento antirretroviral en el año 2004

Knobel, Hernando; Escobar, Ismael; Polo, Rosa; Ortega, Luis; Martin-Conde, Maite; Casado, José L.; Codina, C; Fernández, J.A. Canelas; Galindo, M.a José; Ibarra, O.; Llinas, Monserrat; Miralles, Celia; Riera, Melcior; Fumaz, Carmina R.; Segador, Aurea; Segura, Ferrán; Chamorro, Lourdes

doi:10.1157/13073149

Cited by 41 publications

(35 citation statements)

References 76 publications

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“…4 Nonadherence to treatment in chronic processes in general is a well-known problem, and the reasons would seem to be multiple, including factors relating to health (quality of the health/patient relation), and individual, sociodemographic, psychosocial, and clinical factors (type of disease, unwanted side effects, or complexity of the therapy). 5,6 In 2003 Spain had a prison population of 54,497 inmates. 7 This large population is affected by various health problems, the most frequent being those of parenteral transmission [hepatitis C virus (HCV) and mainly HIV], as well as tuberculosis, psychiatric illnesses, and drug abuse.…”

Section: Introductionmentioning

confidence: 99%

Adherence to Antiretroviral Treatment in Prisons

Blanco

Ruiz-Pérez²,

Lima³

et al. 2005

AIDS Research and Human Retroviruses

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The effectiveness of antiretroviral drugs is closely linked to the degree of adherence. The prison environment has specific characteristics that may affect adherence in HIV-positive patients, so that it may not be possible to extrapolate factors associated with nonadherence in HIV+ patients outside prison. The objective was to analyze the prevalence of nonadherence to antiretroviral treatment in three Spanish prisons, and to examine the relation between a large group of factors and nonadherence to the medication. A cross-sectional study of all patients receiving antiretroviral treatment was done. Adherence was evaluated using a validated questionnaire (SMAQ). The prevalence of nonadherence was 54.8%, and the factors independently associated with nonadherence were having difficulties in taking the medication, feeling completely or largely unable to follow the medication, classifying the food as "bad", mentioning not having anyone concerned for them outside prison, suffering anxiety or depression in the last week, and having the flexibility of the prison staff opening their cell in the event of them forgetting their medication.

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Section: Introductionmentioning

confidence: 99%

Adherence to Antiretroviral Treatment in Prisons

Blanco

Ruiz-Pérez²,

Lima³

et al. 2005

AIDS Research and Human Retroviruses

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“…In a recent study, the factors associated with poor adherence in 169 patients with chronic myeloid leukemia who were treated with imatinib were: demographic variables such as age, living alone and being male; treatment variables such as duration of treatment and different combinations for a dose; and the patient–physician relationship 76. The same risk factors have been published in the recommendations of the Spanish AIDS groups, including adverse events secondary to treatment 77. When feasible, on-site pharmacies and consultations with a pharmacist should be encouraged because they may facilitate adherence 78…”

Section: Adherence and Patient Preferencesmentioning

confidence: 97%

Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations

García¹,

Clopés²,

Bruna³

et al. 2009

CMR

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Chemotherapy is assuming an increasingly important role in the treatment of malignant gliomas, of which temozolomide (TMZ) is a key part. TMZ belongs to a class of second-generation imidazotetrazinone prodrugs that exhibit linear pharmacokinetics and do not require hepatic metabolism for activation to the active metabolite. New intravenous (iv) TMZ formulations have recently been approved based on studies of bioequivalence between iv and oral TMZ. The efficacy of TMZ was initially evaluated in patients with recurrent disease but phase II and III trials in newly diagnosed gliomas are available. The results of a large phase III trial that compared RT alone vs RT concomitant with oral TMZ created a new standard of adjuvant treatment. Efficacy data for iv TMZ on which its approval was based are those extrapolated from clinical trials with oral TMZ. No comparative data are available on the differences in tolerability and patient satisfaction between oral and iv formulations of TMZ, or for quality of life. New oral formulations could encourage the adherence of patients to treatment. Although patients presumably would prefer oral treatment, iv formulations may be an alternative in noncompliant patients or patients for whom good adherence could not be expected.

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“…Aprovechando la continuidad en las visitas al médico de familia, se puede hacer un buen seguimiento del paciente y elaborar un plan de cuidados en colaboración con el propio paciente reforzando las medidas preventivas para alcanzar una buena calidad de vida (19,(23)(24)(25):…”

Section: Seguimientounclassified

Papel del médico de familia en el manejo de la infección por VIH

Figuero

Luque²,

Bouza

et al. 2007

An. Med. Interna (Madrid)

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INTRODUCCIÓNHan pasado 25 años desde que en 1981 se publicaron los primeros casos de sida (1). En este tiempo más de 60 millones de personas se han infectado y actualmente el programa de sida de las Naciones Unidas estima que 40,3 millones de personas viven con el virus de la inmunodeficiencia humana (VIH) y que durante 2005 se registraron 4,9 millones de nuevas infecciones (2). Esto da idea del impacto de la enfermedad convirtiendo al VIH/sida en una de las principales causas de [0212-7199 (2007) 24: 8; pp 399-403] ANALES DE MEDICINA INTERNA

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Recomendaciones GESIDA/SEFH/PNS para mejorar la adherencia al tratamiento antirretroviral en el año 2004

Cited by 41 publications

References 76 publications

Adherence to Antiretroviral Treatment in Prisons

Adherence to Antiretroviral Treatment in Prisons

Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations

Papel del médico de familia en el manejo de la infección por VIH

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