Recommandations en Onco-Urologie 2010 : Cancer de la prostate

Salomon, Laurent; Azria, D.; Bastide, C.; Beuzeboc, Philippe; Cormier, L.; Cornud, F.; Eiss, D.; Eschwège, P.; Gaschignard, N.; Hennequin, Christophe; Molinié, Vincent; Artus, P. Mongiat; Moreau, Jean‐Luc; Péneau, M.; Peyromaure, M.; Ravery, V.; Rébillard, Xavier; Richaud, Pierre; Rischmann, P.; Rozet, F.; Staerman, F.; Villers, Arnauld; Soulié, M.

doi:10.1016/s1166-7087(10)70042-7

Cited by 103 publications

(20 citation statements)

References 299 publications

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“…Nevertheless, these studies have in common difficulty assessing regional lymphnodes (NX). Indeed, only the dissection can confirm nodals status of prostate cancer [16]. Difficulty making a clear distinction between the proportions of the three categories of D'Amico is due to lack of sensitivity and specificity of the bladder and prostate ultrasound [17].…”

Section: Discussionmentioning

confidence: 99%

Clinical Stage Evaluation at Diagnosis of Prostate Cancer at Urology-Andrology Clinic Cnhu-Hkm Cotonou

Pascal¹,

Avakoudjo²,

Yde³

et al. 2015

OJU

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Aims: To evaluate the clinical stage at diagnosis of prostate cancer. Materials and Methods: This study was retrospective and descriptive from January 2008 to June 2013. Patients who were diagnosed with prostate cancer wereinvolved and confirmed by clinical examination anatomopathological screening. They also realized a total serum PSA, a bladder-prostatic and abdominal ultrasound. Results: Average age was seventy years, ranging from fifty years to seventy years. The general status of our patients was satisfactory in 78% of cases. Main symptoms were dysuria and frequencyin 96% and 86%, respectively. Family past history of prostate cancer were found in 24% of cases. Twenty-three patients (43%) had a total serum PSA ≥ 100 ng/ml. Adenocarcinoma was the main histological type. Grades 1 and 4 were the most frequent. Thirty-three patients (66%) had a Gleasonscore betwen [2]-[6]. Forty-four patients (88%) had locally advanced and metastatic desease. The D'Amico score was identified in six patients but 3 and 2 patients were low risk and intermediate riskrespectively. Finally, 1 patient was high risk. Conclusion: Prostate cancer remains elderly man cancer. It was discovered in locally advanced and metastatic desease in this series. This diagnosis was late in the majority of cases.

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Section: Discussionmentioning

confidence: 99%

Clinical Stage Evaluation at Diagnosis of Prostate Cancer at Urology-Andrology Clinic Cnhu-Hkm Cotonou

Pascal¹,

Avakoudjo²,

Yde³

et al. 2015

OJU

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“…Il est admis aujourd'hui que les tumeurs cT3a (extension extracapsulaire limitée) font partie des tumeurs à haut risque [16,29].…”

Section: Définitionsunclassified

“…Il est recommandé de faire l'IRM six semaines après les biopsies, mais l'IRM peut être faite avant les biopsies si le TR est évocateur d'un stade clinique T2 ou T3a [29]. La séquence T1 permet de différencier un artéfact lié aux biopsies (hémorragie) d'un aspect tumoral.…”

Section: Bilan D'extensionunclassified

“…La scintigraphie osseuse est recommandée pour les CPHR, surtout si le PSA est supérieur à 20 ng/ml et/ou le score de Gleason est supérieur ou égal à 8 [16,20,29]. L'IRM permet d'étudier la moelle osseuse du corps entier avec une sensibilité (100 %) et une spécificité (90 %) supérieures à celles de la scintigraphie, sauf au niveau des côtes et de la voûte crânienne [19].…”

Section: éValuation Osseuseunclassified

“…Un traitement complémentaire par radiothérapie et/ou hormonothérapie sera discuté en fonction des résultats anatomopathologiques et du PSA postopé-ratoire [16,[29][30][31]. Les patients pré-sentant un CPHR doivent être informés de cette approche multimodale décidée en RCPO.…”

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Management of high-risk prostate cancer: surgery or radiotherapy with hormonal treatment

Soulié

Richaud

2012

Oncologie

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Among the different treatment options recommended for high-risk prostate cancer (HRPC), radical prostatectomy (RP) is recognized along with radiotherapy, but its role is still controversial in monotherapy and difficult to evaluate in combined treatments. The results of clinical trials combining an external radiotherapy with a long-term androgen deprivation in locally advanced tumours sustain the principle of a multidisciplinary management in HRPC. Clinical and histological data associated with the MRI assessment remain essential and enhance the preoperative multidisciplinary decision, especially regarding nodal and distant metastases. An enlarged RP with an extended pelvic lymphadenectomy can be considered a viable alternative to radiotherapy and hormonal therapy. Morbidity of the procedure is similar to RP for organ-confined tumours, despite more erectile dysfunction due to non-sparing RP is observed in most of the cases. Oncological results of recent studies show 10-year and 15-year specific survival rates to be around 85% and 75% respectively, similar to those with hormonoradiotherapy.

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Prise en charge thérapeutique des cancers de prostate

Beuzeboc

Ccafu²

2011

Thérapeutique Du Cancer

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Recommandations en Onco-Urologie 2010 : Cancer de la prostate

Cited by 103 publications

References 299 publications

Clinical Stage Evaluation at Diagnosis of Prostate Cancer at Urology-Andrology Clinic Cnhu-Hkm Cotonou

Clinical Stage Evaluation at Diagnosis of Prostate Cancer at Urology-Andrology Clinic Cnhu-Hkm Cotonou

Management of high-risk prostate cancer: surgery or radiotherapy with hormonal treatment

Prise en charge thérapeutique des cancers de prostate

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