Recommandations sur l’antibioprophylaxie en chirurgie et médecine interventionnelle

Dransart-Raye, Ophélie; Roussat, Marie-Odile

doi:10.1016/j.oxy.2018.02.004

Cited by 1 publication

(1 citation statement)

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“…All endo-urological interventions with a sterile urine culture require intraoperative antibiotic prophylaxis, and French guidelines propose the use of first-or second-gen-Urol Int 2022;106:1272-1278 DOI: 10.1159/000522223 eration cephalosporin (cefazoline, cefamandole, or cefuroxime) in the absence of allergies or gentamicin in the event of an allergy. It should be started 30 min before the beginning of the procedure [3].…”

Section: Introductionmentioning

confidence: 99%

Use of Antibiotic Prophylaxis for Polymicrobial Urine Culture before Urological Surgery: A Pilot Study

et al. 2022

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Introduction: Preoperative polymicrobial urine cultures are common, but the associated risk of nosocomial infection is currently unknown. We aimed to analyze the risk of postoperative infection in patients with preoperative polymicrobial urine cultures. Methods: This was a prospective cohort study conducted from November 2018 to October 2020. Polymicrobial urine cultures were defined by at least the presence of 3 bacteria without leukocyturia threshold on two consecutive samples in the month preceding the surgical procedure. Data on postoperative infections were collected during hospitalization until day 30. A postoperative infection was defined by the occurrence of clinical signs (fever, chills, and suppurated process on the surgical site) associated with the prescription of an antibiotic therapy. Results: Sixty-eight patients were included, and seven developed a postoperative infection with a microbe identified in blood or urine cultures. There was a significant association between leukocyturia ≥104 (p = 0.02) and the administration of intraoperative antibiotic prophylaxis (p < 0.001). In contrast, there was no significant association between postoperative infections for patients with polymicrobial preoperative urine cultures and having received or not an empirical antibiotic therapy. Conclusion: The rate of postoperative infection in patients with polymicrobial urine culture before urological procedure was 10.2%. Further studies are needed to assess the antibiotic prophylaxis to be used in this situation.

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Section: Introductionmentioning

confidence: 99%