Objectives.
Basal interventricular septal (IVS) hypertrophy (BSH) with reduced basal IVS contraction and IVS to aorta angle is frequently associated with aortic stenosis (AS). The shape of BSH suggests compression from longitudinally elongated ascending aorta, causing basal IVS thickening and contractile dysfunction, which further suggests the possibility of aortic wall shortening to improve the BSH. Surgical aortic valve replacement (SAVR), as opposed to transcatheter AVR (TAVR), includes aortic wall shortening by incision and stitching on the wall and may potentially improve BSH. We hypothesized that BSH configurations and its contraction improves after SAVR, as opposed to TAVR, in patients with AS and associated BSH.
Methods.
In 32 patients with SAVR and 36 with TAVR for AS, regional wall thickness and systolic contraction (longitudinal strain) of 18 left ventricular (LV) segments as well as IVS to aorta angle were measured by echocardiography.
Results.
After SAVR, basal IVS to averaged LV wall thickness ratio, basal IVS strain, and IVS to aorta angle significantly improved (1.11±0.24 to 1.06±0.17, −6.2±5.7 to −9.1±5.2 %, 115±22 to 123±14 degree, p<0.001, respectively). Contractile improvement in basal IVS was correlated with pre-SAVR BSH (basal IVS to averaged LV wall thickness ratio or IVS to aorta angle: r=0.47 and 0.49, p<0.01, respectively). In contrast, these BSH indices did not improve after TAVR.
Conclusions.
In patients with AS, SAVR as opposed to TAVR improves associated BSH and its functional impairment.