“…The capillaries of the glymphatic system are not directly visible either in the raw video data, see Figure 3 A, or in the mean obtained by using a commercial deep learning denoising autoencoder from the “Deep Learning Toolbox” of MATLAB ( Zhang et al, 2017 ; Berghout et al., 2020 , Berghout, 2021 ), see Figure 3 B. Application of the common GMM entropy ( Zoran and Weiss, 2011 ; Bouman et al., 2018 ; The Event Horizon Telescope Collaboration, 2019a ; Greggio et al., 2012 ) does allow to visualize only surface capillaries, see Figure 3 C. The deeper lying bulk capillaries are not directly visible and can only be revealed through latent effects. As can be seen from the Figure 3 D, applying the latent entropy measure one can extract and visualize the capillary pattern, including the bulk ones.…”