Recording monophasic action potentials using a platinum-electrode ablation catheter

Abstract

(1) Platinum electrodes can be used for timely recording of MAPs in patients. (2) It is feasible to record MAPs and deliver radiofrequency currents via the same platinum-tip electrode. These findings suggest that MAP-guided catheter ablation is technically possible.

Recording Atrial Monophasic Action Potentials Using Standard Pacemaker Leads:

“…The attempt to use pacemaker leads or catheters for MAP recordings is not new. Advanced pacemaker lead technology has been used to record MAP in the ventricle 10 and ablation catheters have been used for MAP recording even in the atrium 11 …”

“…Advanced pacemaker lead technology has been used to record MAP in the ventricle 10 and ablation catheters have been used for MAP recording even in the atrium. 11 Unlike transmembrane action potential (AP) amplitude which is measuredbetween resting potential and peak of the upstroke, MAP amplitude is defined as the difference in millivolts from baseline to the crest of the MAP plateau. Defining the plateau crest is hampered by the more triangular shape of action potentials in human atrial muscle.…”

“…Far-field signals from the ventricle are known to interfere with atrial sensing. 11 Due to slow AV conduction late far-field signals could superimpose on the late repolarization phase of atrial MAPlike electrograms. The present study group included some patients with AV block II (Mobitz) and III when at rest.…”

Non-fluoroscopic catheter-based mapping systems in cardiac electrophysiology—from approved clinical indications to novel research usage

“…We first validated the possibility of recording MAPs using a conventional platinum electrode ablation catheter (18) and then verified the feasibility of recording MAPs using a CARTO sensor-equipped catheter.…”

“…A prerequisite for the use of the CARTO system as a means to evaluate repolarization is that the MAP recording catheter must be locatable by the system. We first validated the possibility of recording MAPs using a conventional platinum electrode ablation catheter (18) and then verified the feasibility of recording MAPs using a CARTO sensor-equipped catheter. To improve the quality of the MAP recording and to facilitate the mapping procedure, a special Navi-star catheter with a modified tip was developed for MAP mapping using the CARTO system (19) (Figure 3).…”