“…Moreover, since the increase in the RH perfusion (i.e., hypothetical right-sided release from inhibition) was associated both with significant improvement of language functioning (Table 2 and Table 3) and profound deficiency of the initial LH perfusion in the present study, we could expect, surprisingly, a better prognosis for aphasia in patients with a large brain lesion. Obviously, data from the literature suggest the reverse: Aphasic patients whose neuroimaging scans show large lesions are less likely to recover than those with smaller lesions (Sarno, 1998). In addition, we noted a relationship between degree of cerebral hypoperfusion and severity of aphasia, i.e., large brain infarcts produced language problems to a greater degree than smaller infarcts.…”