Recovery of oculomotor nerve palsy after endovascular management of posterior communicating artery aneurysms

Abstract

Background: Oculomotor nerve palsy (ONP) is a common clinical presentation of posterior communicating artery (PcomA) aneurysms. It remains unclear if patients have a better rate of recovery after surgical clipping or endovascular coiling.Objectives: The main objectives of this study were to assess the overall rate of ONP recovery after endovascular coiling of PcomA aneurysms, as well as to determine the associated predictive factors of oculomotor nerve recovery.Method: We retrospectively evaluated the demographic, clinical, and radiological characteristics and the outcome of consecutive patients presenting with PcomA aneurysms treated by endovascular coiling from January 2012 to November 2016 with at least 1 year clinical and radiological follow-up. Statistical analysis was applied to determine the association between ONP recovery and the demographic, clinical and radiological variables.Results: A total of 91 patients with PcomA aneurysms were treated endovascularly. Thirty-four patients (22 women and 12 men) with ONP related to PcomA aneurysms were included. The mean age of the patients was 49.8 years. Subarachnoid haemorrhage was present in 27 patients. The mean aneurysm size was 6.7 mm. The overall rate of recovery was 88.2%. Complete nerve recovery was seen in 16 (47%) patients and partial recovery was observed in 14 (41.2%) patients, whilst 4 (11.8%) patients remained unchanged after treatment. The non-posterolateral direction of the aneurysm showed a tendency towards better recovery compared to the posterolateral projection (p = 0.06).Conclusion: Endovascular coiling of PcomA aneurysms in patients with ONP resulted in a cure or improvement of oculomotor nerve dysfunction in the majority of patients.

The Telltale Botox: Botulinum Toxin Injection by an Expert Hand as an Intracranial Aneurysm Detector

“…The patient experienced complete resolution of the clinical symptoms after endovascular treatment, an occurrence reported in 88.3% of patients. 13 The main limitation of our experience is related to the reporting of a single, highly unusual case, with the difficulty of inferring general, therapeutic, or management considerations about this clinical issue.…”

“…The patient experienced complete resolution of the clinical symptoms after endovascular treatment, an occurrence reported in 88.3% of patients. 13 …”

Effects of endovascular treatment and prognostic factors for recovery of oculomotor nerve palsy caused by posterior communicating artery aneurysms: a multi-center retrospective analysis

“…The aneurysmal direction might affect the occurrence and recovery of ONP anatomically. Abdurahman et al reported that the non-posterolateral direction of the aneurysm showed a tendency towards better recovery compared to the posterolateral projection [ 25 ], while in another study there was no correlation between aneurysmal direction and ONP recovery [ 26 ]. In our study, posterior-lateral-inferior direction of aneurysm dome showed a tendency towards unpleasant ONP recovery compared to other directions in univariate analysis, however, there was no significant difference in multivariate analysis.…”