2005
DOI: 10.1196/annals.1325.039
|View full text |Cite
|
Sign up to set email alerts
|

Recovery of Peripheral Versus Central Nerves Identified by Saccadic Velocity After Abducens Neuropathy

Abstract: The abducens is the motor nerve with the most substantial course, both within and outside the brain and it innervates only one muscle. Sixth nerve palsy affords an opportunity to compare recovery after central versus peripheral nerve damage by assessing the dynamics of abduction. Horizontal saccade peak velocities and durations in 14 patients with unilateral peripheral sixth nerve palsies (5 acute, 9 chronic) are compared with those in 5 patients with central sixth nerve palsies (2 acute, 3 chronic) and with t… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
4
0

Year Published

2006
2006
2022
2022

Publication Types

Select...
3
1

Relationship

1
3

Authors

Journals

citations
Cited by 4 publications
(4 citation statements)
references
References 35 publications
0
4
0
Order By: Relevance
“…Those interested in facial nerve regeneration depended upon conclusions drawn from models of nerves in the extremities, most notably the rat sciatic nerve 6–14. However, over the past decade the regenerative neurobiology of motor versus sensory versus mixed nerves has become widely appreciated,15, 16 and the potential biologic differences between cranial and peripheral nerves has likewise been acknowledged 17. Thus, the importance of an animal facial nerve injury model for attempting to understand and manipulate facial nerve regeneration has been recognized, and researchers have responded with the development of small mammal facial nerve injury models 18–20…”
Section: Introductionmentioning
confidence: 99%
“…Those interested in facial nerve regeneration depended upon conclusions drawn from models of nerves in the extremities, most notably the rat sciatic nerve 6–14. However, over the past decade the regenerative neurobiology of motor versus sensory versus mixed nerves has become widely appreciated,15, 16 and the potential biologic differences between cranial and peripheral nerves has likewise been acknowledged 17. Thus, the importance of an animal facial nerve injury model for attempting to understand and manipulate facial nerve regeneration has been recognized, and researchers have responded with the development of small mammal facial nerve injury models 18–20…”
Section: Introductionmentioning
confidence: 99%
“…Preliminary results have been published as an extended abstract. 7 Methods. Clinical assessment and imaging.…”
mentioning
confidence: 99%
“…Patients with central palsy, both acute and chronic, had slow abducting saccades but in patients with peripheral palsy, abducting saccadic speed became normal in the face of persistent esotropia when tested 2 months after the onset of diplopia, (Sharpe et al, 2005;Wong et al, 2006). Recovery of abducting saccadic velocity in the paretic after peripheral neuropathy may be due to partial regeneration of axons or myelin of the peripheral nerve.…”
Section: Recovery Of Saccadic Velocity In Vith Nerve Palsymentioning
confidence: 99%
“…All measurements were performed for saccades to targets10 degrees left and right of orbital midposition, within the range of limited duction caused by the palsy. Serial recordings were performed on those two patients with acute, central fascicular palsy, at presentation and at 2 months after symptom onset (Sharpe et al, 2005;Wong et al, 2006). Recordings from 10 normal adult subjects provided control data.…”
Section: Methodsmentioning
confidence: 99%