Recruiting long-term survivors of European Organisation for Research and Treatment of Cancer phase III clinical trials into quality of life studies: Challenges and opportunities

Leeuwen, Marieke van; Efficace, Fabio; Fosså, Sophie D.; Bolla, M.; Giorgi, Ugo De; Wit, Ronald de; Holzner, Bernhard; Poll‐Franse, Lonneke V. van de; Poppel, Hendrik Van; White, Jeff; Collette, Laurence; Osanto, Susanne; Aaronson, Neil K.

doi:10.1016/j.ejca.2014.04.018

Cited by 5 publications

(3 citation statements)

References 23 publications

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“…As far as we know, QoL evaluations in long-term TCSs have only been conducted in single country trials. Recently, however, some studies have begun assessing the feasibility of collecting QoL data among TCSs recruited from different countries (116, 117). To better understand the impact of TC on QoL it is important to know how sociocultural differences in sexuality, masculinity and fertility influence the survivors.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial Issues in Long-Term Survivors of Testicular Cancer

et al. 2019

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Testicular cancer is the most frequent tumor in young males aged 15–39 years. As cure rates are currently around 90%, the prevalence of survivors is increasing. However, a disease-free condition does not necessarily correspond to a life free of physical and psychosocial health problems. The aim of this review was to explore psychosocial morbidity among testicular cancer survivors. A literature search was conducted in three electronic databases (PubMed, Medline, and Embase). The results of the search on cancer survivors were then combined with those of the search on psychosocial concerns and work performance. Eighty-four publications met the inclusion criteria. Physical, psychological, work-related problems and changing perspectives about work and life in general influenced life and career decisions among testicular cancer survivors. Individual health, sexual relationships and work problems, affect several important aspects of survival and significantly influence the QoL of long-term survivors.

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Section: Discussionmentioning

confidence: 99%

Psychosocial Issues in Long-Term Survivors of Testicular Cancer

et al. 2019

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“…In parallel, there are many unanswered research questions relating to long-term gynecologic cancer survivors which need a new generation of dedicated studies. Examples include, i) how to better coordinate and deliver information, ii) how to prevent and treat long-term side effects, iii) how to predict patients who are likely to experience long-term side effects [7,8].…”

Section: Introductionmentioning

confidence: 99%

GCIG-Consensus guideline for Long-term survivorship in gynecologic Cancer: A position paper from the gynecologic cancer Intergroup (GCIG) symptom benefit committee

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et al. 2022

Cancer Treatment Reviews

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“…Alternatively, a cohort study that only included men with a history of testicular cancer might enable the study of factors that are related to the occurrence of a contralateral testicular cancer. With this regard, some cohorts of testicular cancer survivors have already been established (Brabrand et al ., ; Beard et al ., ; van Leeuwen et al ., ).…”

Section: Summary Of the 2‐h Post‐workhop Meetingmentioning

confidence: 97%

A survey of etiologic hypotheses among testicular cancer researchers

et al. 2014

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Basic research results can provide new ideas and hypotheses to be examined in epidemiological studies. We conducted a survey among testicular cancer researchers on hypotheses concerning the etiology of this malignancy. All researchers on the mailing list of Copenhagen Testis Cancer Workshops and corresponding authors of PubMed-indexed articles identified by the search term “testicular cancer” and published within 10 years (in total 2750 recipients) were invited to respond to an e-mail based survey. Participants of the 8th Copenhagen Testis Cancer Workshop in May 2014 were subsequently asked to rate the plausibility of the suggested etiologic hypotheses on a scale of 1 (very implausible) to 10 (very plausible). This report describes the methodology of the survey, the score distributions by individual hypotheses, hypothesis group and the participants’ major research fields, and discuss the hypotheses that scored as most plausible. We also present plans for improving the survey that may be repeated at a next international meeting of experts in testicular cancer. Overall 52 out of 99 (53%) registered participants of the 8th Copenhagen Testis Cancer Workshop submitted the plausibility rating form. Fourteen out of 27 hypotheses were related to exposures during pregnancy. Hypotheses with the highest mean plausibility ratings were either related to prenatal exposures or exposures that might have an effect during pregnancy and in post-natal life. The results of the survey may be helpful for triggering more specific etiologic hypotheses that include factors related to endocrine disruption, DNA damage, inflammation, and nutrition during pregnancy. The survey results may stimulate a multidisciplinary discussion about new etiologic hypotheses of testicular cancer.

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Recruiting long-term survivors of European Organisation for Research and Treatment of Cancer phase III clinical trials into quality of life studies: Challenges and opportunities

Cited by 5 publications

References 23 publications

Psychosocial Issues in Long-Term Survivors of Testicular Cancer

Psychosocial Issues in Long-Term Survivors of Testicular Cancer

GCIG-Consensus guideline for Long-term survivorship in gynecologic Cancer: A position paper from the gynecologic cancer Intergroup (GCIG) symptom benefit committee

A survey of etiologic hypotheses among testicular cancer researchers

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