Recruiting older adults for clinical trials

Adams, Janet; Silverman, Myrna; Musa, Donald; Peele, Pamela B.

doi:10.1016/s0197-2456(96)00132-8

Cited by 77 publications

(69 citation statements)

References 27 publications

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“…10,22,23 But by recruiting patients from our own practices we were able to avoid a barrier that has been encountered when recruiting for treatment studies by advertisement or mailing to randomly selected people, namely, a recommendation against participation by the woman's personal physician. 4,24 …”

Section: Discussion Recruitmentmentioning

confidence: 99%

“…Recruiting a representative sample that includes adequate numbers of older women is difficult and costly: recruitment costs are estimated at $100 22 to $300 9 per participant and require an estimated 31 hours of staff time per recruited patient. 4 Too often, recruitment strategies are poorly planned, underfunded, and have to be changed as the trial progresses.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Enhancing Participation of Older Women in Surgical Trials

Goode

FitzGerald

Richter

et al. 2008

Journal of the American College of Surgeons

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Section: Discussion Recruitmentmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Enhancing Participation of Older Women in Surgical Trials

Goode

FitzGerald

Richter

et al. 2008

Journal of the American College of Surgeons

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“…There were considerable difficulties in recruiting only through primary care, and the recognition of carers in primary care is an ongoing area of concern. 93 A move towards multiple strategies, as recommended by Adams and colleagues 94 and DiBartolo and McCrone, 95 improved overall recruitment, but barriers remained, including non-identification with the term 'carer', nonfacilitative gatekeepers, burden of written information and a disperse client group. 96 Reflecting on the recruitment activity, from the identification of potential participants through to randomisation, it appears that the recruitment strategy that produced the highest number of expressions of interest was not necessarily the most productive strategy for identifying eligible participants.…”

Section: Factors To Consider In Carer Support Research Recruitmentmentioning

confidence: 99%

Does befriending by trained lay workers improve psychological well-being and quality of life for carers of people with dementia, and at what cost? A randomised controlled trial

Charlesworth¹,

Shepstone²,

Wilson³

et al. 2008

Health Technol Assess

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“…Kolanowski et al [34], reported strategies that address participant and family barriers including early site evaluation and strong communication approaches with staff, participants, and families. It has also been reported that a face-to-face approach is more effective than recruiting from other sources and helped to reduce the uncertainty that older adults felt about participating in research study [2].…”

Section: Discussionmentioning

confidence: 99%

Recruiting Older People at Nutritional Risk for Clinical Trials: What Have We Learned?

Naganathan

Piantadosi

Chapman

et al. 2017

Innovation in Aging

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Background: The difficulty of recruiting older people to clinical trials is well described, but there is limited information about effective ways to screen and recruit older people into trials, and the reasons for their reluctance to enrol. This paper examines recruitment efforts for a community-based health intervention study that targeted older adults. Methods: One year randomized control trial. Undernourished men and women, aged ≥ 65 years and living independently in the community were recruited in three Australian states. Participants were allocated to either oral testosterone undecanoate and high calorie oral nutritional supplement or placebo medication and low calorie oral nutritional supplementation. Hospital admissions, functional status, nutritional health, muscle strength, and other variables were assessed. Results: 4023 potential participants were identified and 767 were screened by a variety of methods: hospital note screening, referrals from geriatric health services, advertising and media segments/appearances. 53 participants (7% of total screened) were recruited. The majority of potentially eligible participants declined participation in the trial after reading the information sheet. Media was the more successful method of recruiting, whereas contacting people identified by screening a large number of hospital records was not successful in recruiting any participants.

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Recruiting older adults for clinical trials

Cited by 77 publications

References 27 publications

Enhancing Participation of Older Women in Surgical Trials

Enhancing Participation of Older Women in Surgical Trials

Does befriending by trained lay workers improve psychological well-being and quality of life for carers of people with dementia, and at what cost? A randomised controlled trial

Recruiting Older People at Nutritional Risk for Clinical Trials: What Have We Learned?

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