2004
DOI: 10.1128/jvi.78.4.1605-1615.2004
|View full text |Cite
|
Sign up to set email alerts
|

Recruitment of Replication Protein A by the Papillomavirus E1 Protein and Modulation by Single-Stranded DNA

Abstract: With the exception of viral proteins E1 and E2, papillomaviruses depend heavily on host replication machinery for replication of their viral genome. E1 and E2 are known to recruit many of the necessary cellular replication factors to the viral origin of replication. Previously, we reported a physical interaction between E1 and the major human single-stranded DNA (ssDNA)-binding protein, replication protein A (RPA). E1 was determined to bind to the 70-kDa subunit of RPA, RPA70. In this study, using E1-affinity … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

1
88
0
1

Year Published

2005
2005
2023
2023

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 98 publications
(90 citation statements)
references
References 86 publications
1
88
0
1
Order By: Relevance
“…This process could then load successive RPA molecules on the emerging ssDNA . A similar process may coordinate the formation of the prereplication complex by the papillomavirus E1 helicase as well (Loo and Melendy 2004).…”
Section: Implications Of Conformational Change For Rpa Functionmentioning
confidence: 99%
See 4 more Smart Citations
“…This process could then load successive RPA molecules on the emerging ssDNA . A similar process may coordinate the formation of the prereplication complex by the papillomavirus E1 helicase as well (Loo and Melendy 2004).…”
Section: Implications Of Conformational Change For Rpa Functionmentioning
confidence: 99%
“…The loading of RPA onto DNA has been investigated in the SV40 and papillomavirus replication model systems (Loo and Melendy 2004;Jiang et al 2006). During the initiation of SV40 replication, the unwinding of the origin of replication is coupled to RPA loading by the Tag helicase (Jiang et al 2006).…”
Section: Implications Of Conformational Change For Rpa Functionmentioning
confidence: 99%
See 3 more Smart Citations