Rectal localized giant inflammatory polyposis with indeterminate colitis

Abstract

Only two cases of rectal giant inflammatory polyposis with ulcerative colitis have been reported in the English literature and both concern children. This is the first report of a case of localized giant inflammatory polyposis of the rectum in an adult with indeterminate colitis. A 71-year-old man underwent sigmoidectomy due to stenosis of the sigmoid colon. Final histological diagnosis was indeterminate colitis. Three years following the first operation, a rectal tumor with giant polyposis was observed, and abdominoperineal resection was performed. Macroscopic and microscopic examination indicated a localized giant inflammatory polyposis of the rectum.

Giant filiform polyposis with high-grade dysplasia: A case report and review of the literature

“…Eighteen cases (full text available) of filiform polyposis originated from the normal colon with no history of IBD, of which two (11%) cases were associated with adenocarcinoma ( Table 1 ) [ 2 , [6] , [7] , [8] , [10] , [11] , [12] , [13] , [14] , [15] , [16] ]. Eighty-six cases of filiform polyposis were associated with IBD, of which, 48 and 38 were associated with UC and Crohn's disease (CD), respectively ( Table 2 ) [ 3 , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] ]. As shown in Table 2 , there were no noticeable differences in clinical features, such as location of occurrence, age of onset, and symptoms, between UC and CD.…”

“…There was one case [ 17 ] of adenocarcinoma in UC (2.0%) and one case [ 17 ] of dysplasia in CD (2.6%). Clinicopathological findings of obstructive GFP cases with UC are summarised in Table 3 [ 3 , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] ]. The most frequent site of occurrence was the transverse colon in eight of the 11 (72.7%) cases, as in this patient.…”