Rectal metastases from small cell lung cancer

Johnson, Alison; Allen, M. Brandon

doi:10.1016/0954-6111(95)90252-x

Cited by 16 publications

(12 citation statements)

References 5 publications

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“…Abdominal pain due to intestinal tract obstruction was the most frequent initial clinical symptom of metastatic colon cancer from primary malignant lung neoplasms [19, 25, 29, 32, 33, 37, 38, 40, 43, 44, 52, 53]. Bloody stool due to either melena or hematochezia was also a common chief complaint [5, 10, 17, 31, 35, 48, 56]. Diagnosis of metastatic lung cancer to the colon by incidental polyp discovery occurs infrequently [10, 18, 42, 55].…”

Section: Discussionmentioning

confidence: 99%

“…Outcomes are based on chief complaints at the time of initial presentation and subsequent surgical intervention [5, 6, 11, 14, 15, 52, 53]. Perforation, obstruction, or hemorrhage have been associated with less favorable outcomes [6, 11, 19, 22, 48, 52, 53]. Early detection and surgical intervention have been postulated to improve survival [25].…”

Section: Discussionmentioning

confidence: 99%

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Bowel obstruction caused by colonic metastasis of lung adenocarcinoma: a case report and literature review

et al. 2019

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Introduction Lung cancer is the most common cause of cancer-related deaths globally. Metastatic disease is often found at the time of initial diagnosis in the majority of lung cancer patients. However, colonic metastases are rare. This report describes an uncommon case of colonic metastasis from lung adenocarcinoma. Case presentation A 64-year-old female presented to her gastroenterologist for progressively worsening abdominal pain and constipation. Exploratory colonoscopy revealed a large rectosigmoid mass resulting in near total rectal occlusion. Her specialist recommended she immediately go to her regional hospital for further workup. On admission, she complained of continued abdominal pain and constipation. Notably, she had a past medical history of non-small cell lung cancer (T1bN3M0 stage IIIB), diagnosed 1 year prior. She was thought to be in remission following radiation and immunotherapy with pembrolizumab. Upon hospital admission, she underwent an urgent colostomy, ileocecectomy and anastomosis, and rectosigmoid mass resection with tissue sampling. Pathology confirmed the diagnosis of colonic metastasis from primary lung adenocarcinoma. Treatment was with systemic chemotherapy followed by localized radiation to the pelvic region was started. She did not respond well to these therapies. Subsequent imaging showed refractory tumor growth in the pelvic region. Treatment could not be completed due to the patient experiencing a debilitating stroke, and she was transitioned to hospice care. Conclusions Clinicians should have a low threshold for intestinal investigation and considerations for colonic metastasis when patients with a history of primary lung cancer have abdominal symptoms.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Bowel obstruction caused by colonic metastasis of lung adenocarcinoma: a case report and literature review

et al. 2019

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“…Two years later, patient presented pain and rectal bleeding and an abdomino perineal resection was performed. The pathology confirmed metastatic small-cell carcinoma and patient died 19 months later of rectal metastasis diagnosis [5]. In a study with autopsy data of 423 patients of primary tumours of the lung, 58 cases (14%) of gastrointestinal metastases were detected, but none of the patientshad rectal involvement [3].…”

Section: Discussionmentioning

confidence: 99%

“…The lung cancer with intestinal metastasis has been reported to have a poor prognosis with median OS of only 4–8 weeks [3–5]. The treatments modalities depend on the nature of presentation and extent of disease.…”

Section: Discussionmentioning

confidence: 99%

Rectal Metastases from Squamous Cell Carcinoma: A Case Report and Review of the Literature

Cedrés

Mulet-Margalef

Montero

et al. 2012

Case Reports in Medicine

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“…There are few reports of primary small cell lung cancer with rectal metastasis. A PubMed search revealed only one report of solitary rectal metastasis from small cell lung cancer in the English literature 12 . A case of initial presentation with solitary metastasis from small cell lung cancer has not been reported previously.…”

Section: Discussionmentioning

confidence: 99%

Solitary rectal metastasis from primary small cell lung carcinoma

et al. 2012

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Lung cancer may rarely appear with a solitary rectal metastasis and no other metastases. We report the first case of primary small cell lung cancer presenting with a solitary rectal metastasis in a 62-year-old man. Chest computed tomography revealed a soft tissue lesion in the subcarinal area. Following bronchoscopic biopsy, the patient was diagnosed with small cell lung cancer. The rectal mass was incidentally found during an imaging study for staging work-up. Histological examination revealed that the rectal mass was consistent with metastasis from small cell lung cancer. We suggest that clinicians should consider the possibility of rectal metastasis in small cell lung cancer patients with rectal masses.

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Rectal metastases from small cell lung cancer

Cited by 16 publications

References 5 publications

Bowel obstruction caused by colonic metastasis of lung adenocarcinoma: a case report and literature review

Bowel obstruction caused by colonic metastasis of lung adenocarcinoma: a case report and literature review

Rectal Metastases from Squamous Cell Carcinoma: A Case Report and Review of the Literature

Solitary rectal metastasis from primary small cell lung carcinoma

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