Rectal obstruction by a giant pharmacobezoar composed of magnesium oxide: Report of a case

Shigekawa, Yoshinobu; Kobayashi, Yasuhito; Higashiguchi, Takashi; Nasu, Toru; Yamamoto, Manabu; Ochiai, Minoru; Tsuji, Takeshi; Yamaue, Hiroki

doi:10.1007/s00595-009-4158-7

Cited by 12 publications

(3 citation statements)

References 17 publications

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“…Although several bezoar case series have been reported from Western countries (3)(4)(5)(6) and South Korea (7), only single case reports or small case series describing a few Japanese patients are available, to our knowledge (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22). In Japan, the epidemiology and etiology of bezoars have not been fully elucidated, and treatment is empirical.…”

Section: Introductionmentioning

confidence: 99%

Clinical Characteristics and Treatment Outcomes of Nineteen Japanese Patients with Gastrointestinal Bezoars

et al. 2014

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Objective To analyze the clinical characteristics of patients with gastrointestinal bezoars and their response to therapy. Patients We retrospectively reviewed the cases of 19 patients diagnosed with gastrointestinal bezoars at the Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences or one of 15 collaborating institutions between December 2004 and August 2013. We investigated the epidemiology and etiology of the gastrointestinal bezoars by determining the gender, age at diagnosis, medical history, symptoms, complications, modalities used for diagnosis, treatments, outcomes and bezoar location, color and contents. Results There were 17 patients with gastric bezoars and two patients with small intestinal bezoars. All patients were 62 years of age or older, except for one case of a trichobezoar in a 10-year-old patient. Some of the patients had a history of surgery of any part of the gastrointestinal tract (n=5) and/or diabetes mellitus (n=2). The two patients with small intestinal bezoars required surgical removal in order to relieve ileus. Approximately one-half of the patients with gastric bezoars had ulcerations in the stomach (9/17 patients, 52.9%) and/or gastrointestinal bleeding (8/17, 47.1%). Endoscopic fragmentation was performed in 10 patients, whereas bezoar dissolution was achieved with a gastroprokinetic agent (n=1) and without any treatment (n=3) in the remaining cases. Conclusion As previously reported, elderly individuals with a positive history of surgery and/or diabetes mellitus were observed in this bezoar patient series. Gastric ulcers and gastrointestinal bleeding were frequently observed. The majority of patients underwent endoscopic fragmentation, while spontaneous resolution of the gastric bezoar was observed in several cases.

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Section: Introductionmentioning

confidence: 99%

Clinical Characteristics and Treatment Outcomes of Nineteen Japanese Patients with Gastrointestinal Bezoars

et al. 2014

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“…Infrared spectroscopy and chemical analyses revealed that the mass's major component was magnesium oxide. Shigekawa et al reported another case of a 75-year-old woman who presented with lower abdominal pain and nausea ( 16 ). The patient had been taking magnesium oxide cathartics for 30 years.…”

Section: Discussionmentioning

confidence: 99%

“…A chemical analysis of the bezoar showed that its major component was magnesium oxide. Previous reports have described patients with magnesium oxide bezoars in the small intestine ( 15 ) and rectum ( 16 ). These bezoars might have been formed in the stomach and migrated into the intestine.…”

Section: Discussionmentioning

confidence: 99%

A Magnesium Oxide Bezoar

et al. 2018

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A 75-year-old Japanese woman presented with nausea and appetite loss. Computed tomography showed a radiopaque substance in the stomach. Esophagogastroduodenoscopy revealed bezoars in the stomach, which were endoscopically retrieved. The bezoars were mainly composed of magnesium and oxide. Although bezoar formation associated with magnesium oxide consumption is infrequently encountered, the present case indicates that pharmacobezoar should be considered among the differential diagnoses in patients who demonstrate a radiopaque mass in the digestive tract and have a history of magnesium oxide use.

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Rectal obstruction by a giant pharmacobezoar composed of magnesium oxide: Report of a case

Cited by 12 publications

References 17 publications

Clinical Characteristics and Treatment Outcomes of Nineteen Japanese Patients with Gastrointestinal Bezoars

Clinical Characteristics and Treatment Outcomes of Nineteen Japanese Patients with Gastrointestinal Bezoars

A Magnesium Oxide Bezoar

Definitive (between-the-eyes) adverse drug reactions

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