The nitrogen removal from wastewater through coupled autotrophic processes of nitritation and anaerobic ammonium oxidation (anammox) is known as deammonification. Single-stage systems are feasible as long as strategies for microaeration and biofilm development are adopted, enabling the formation of aerobic and anoxic zones in the reactor. Deammonification has important economic advantages over conventional nitrification and heterotrophic denitrification processes, especially in the treatment of low C/N wastewater such as landfill leachate. In this context, the objective of the present work was to evaluate the influence of two different microaeration alternatives in the development of a single-stage deammonification process and the landfill leachate treatment. Two continuous reactors, under the same operational conditions, were operated in parallel: reactor with biomass immobilized in polyurethane foam (R1) and reactor with biomass immobilized in silicone membrane (R2). The oxygen diffusion was performed intermittently through a fine bubble diffuser in the R1 reactor, while in the R2 reactor it was carried out continuously without generating bubbles through a bubble-free silicone membrane. Two different stages were evaluated: in stage 1, the feed was carried out with synthetic wastewater; in stage 2, with landfill leachate. The anammox process was observed in both reactors at the beginning of stage 1, after 48 days, but only reached stability after 90 days in R1 and after 83 days in R2. In phase I of stage 1 (NH4 + -Ninfluent = 50 mg N.L -1 ) the reactors R1 and R2 showed an average total nitrogen (TN) removal of 70 ± 5 and 79 ± 3 %, respectively. These same efficiencies were 60 ± 4 and 61 ± 5 % for phase II (NH4 + -Ninfluent = 100 mg N.L -1 ), 76 ± 2 and 69 ± 3 % for phase III-1 (NH4 + -Ninfluent = 250 mg N.L -1 ), and 22 ± 18 and 40 ± 2 % for phase IV (NH4 + -Ninfluent = 500 mg N.L -1 ). In phase IV, the anammox biomass of the R1 reactor was inhibited. The recovery phase (phase III-2, with NH4 + -Ninfluent = 250 mg N.L -1 ) was performed for R1 and R2 reactors, restoring the TN removal to 74 ± 5 e 70 ± 5 %, respectively. After the recovery phase, the TN removal efficiencies were 77 ± 3 and 70 ± 4 % for phase V (NH4 + -Ninfluent = 400 mg N.L -1 ), and 73 ± 3 and 62 ± 3 % for phase VI (NH4 + -Ninfluent = 500 mg N.L -1 ). Stage 1 results denote the complete establishment of the deammonification process. The NO3production and the alkalinity consumption were like to stoichiometric values. Furthermore, FISH microbiological analyzes indicated the coexistence of aerobic and anaerobic ammonium-oxidizing bacteria in both reactors. The R1 reactor showed superior TN removal capacity especially in the final phases of stage 1. However, R2 reactor demonstrated greater stability and resistance to inhibition, due to its innovative microaeration system. In stage 2, the reactors were fed with landfill leachate. In phase I, undiluted landfill 1 leachate was used. In phases II and III, 10 and 15% of the leachate from landfill 2 were...