Recurrence after Different Primary Treatment for Cancer of the Supraglottic Larynx

Squamous Cell Carcinoma of the Head and Neck in Ontario, Canada, and in Southeastern Norway

“…Those identified differences in treatment policies between Norway and the United States for cancer of the larynx have been reported previously by Vermund et al 4 They found that 41% of Wisconsin patients had primary surgery compared with 76% of Norwegian patients who had radiotherapy. Specifically for supraglottic cancer, Vermund et al 5 found that 31% of Wisconsin patients had primary surgery compared with 5% in Oslo, Norway. The differences in treatment practice between Ontario and the United States for both supraglottic cancer and cancer of the glottic larynx have been reported by Groome et al 2,3 They found for supraglottic cancer that in Ontario, 72% of patients had primary radiotherapy, compared with 39% in the United States.…”

“…Another population‐based comparison approach to examine treatment effectiveness is to compare complete patient databases; however, in head and neck oncology, as in randomized trials, such comparison studies have been uncommon. In one instance, Vermund et al 4,5 compared retrospective data on patients with cancer of the larynx from the University of Wisconsin Hospitals with prospective data from the National Radium Hospital in Oslo, Norway, and found significant differences in case mix, treatments, and survival between the two centers. The present study continues our work in population‐based research by comparing two complete prospective databases of patients with squamous cell carcinoma of the head and neck from regional cancer centers in two demographically similar regions within two different countries.…”

Treatment of Squamous Cell Carcinoma of the Oral Cavity, Oropharynx and Hypopharynx An Analysis of 174 Patients in South Western Finland

“…In another study among early tongue carcinoma patients, the recurrence rate after elective neck dissection vs. observation was 9% and 47%, respectively (17). Thus, active treatment of the neck seems warranted (26,27). During follow up, only two of the patients treated with curative intent presented with distant metastases as the only site of disease (Fig.…”

Value of patient-reported symptoms in the follow up of patients potentially cured of laryngeal carcinoma

“…Independent of subsite, the primary treatment was primary radiotherapy with surgery in reserve. 11,12 Since 1996, tumour stage T 1a glottic carcinomas have been preferentially treated with laser surgery. 13…”