Recurrence of Multiple Focal Nodular Hyperplasia in a Young Male Patient

Abstract

Focal nodular hyperplasia (FNH) is the second most common benign hepatic tumor that is usually found in women. Diagnosis of FNH mainly depends on imaging studies such as color Doppler flow imaging, computed tomography, and magnetic resonance imaging. It is characterized by the presence of stellate central scar and is nowadays incidentally diagnosed with increasing frequency due to advances in radiologic imaging technique. FNH typically presents as a single lesion in 70% of cases and generally does not progress to malignancy or recur after resection. Herein, we report a case of a young male patient with recurrent multiple FNH who underwent surgical resection for presumed hepatic adenoma on computed tomography. ( (Fig. 1A, B

Managing Focal Nodular Hyperplasia of the Liver: Surgery or Minimally-invasive Approaches? A Review of the Preferable Treatment Options

“…To date, only one case of recurrent FNH has been described following surgery: a 22-year-old man with a previous history of left-lobe FNH who in fact developed three bilobal lesions 3 years after the first intervention (22). Surgery was the kind of treatment selected also for recurrences.…”

“…Additionally, TAE has also been used as a form of bridge therapy to surgery in selected cases for size reduction and pain control (5,16). Finally, TAE can also be performed in emergency settings as a ready method of arresting hemorrhage arising from a ruptured FNH (arteriographic hemostatic TAE has been applied to only five cases as of 2017) (22)(23)(24)(25). On the other hand, due to the uncertainty about the natural history of FNH and its correlation with HCC, some authors still prefer surgical resection to this minimally invasive approach (15).…”