Recurrence of ventricular arrhythmias in ischaemic secondary prevention implantable cardioverter defibrillator recipients: long-term follow-up of the Leiden out-of-hospital cardiac arrest study (LOHCAT)

Abstract

Ischaemic secondary prevention ICD recipients exhibit a high recurrence rate of potentially life-threatening ventricular arrhythmias. Factors that increase risk can be identified but, even with these factors, it was not possible to distinguish a recurrence-free group.

Primary Prevention Implantable Cardioverter Defibrillator Recipients: The Need for Defibrillator Back-Up After an Event-Free First Battery Service-Life

“…During this follow‐up, Borleffs et al described a 9% increase in first appropriate ICD therapy from the fifth to the eighth year following implantation. In addition, the authors state that during this long period of follow‐up, 12% of patients experiencing a life‐threatening VA had their first occurrence more than 5 years after implantation 19 . Finally, in a study by Tandri et al , incidences of appropriate therapy after 5 event‐free years were assessed in primary and secondary prevention ICD recipients.…”

Clinical prediction model for death prior to appropriate therapy in primary prevention implantable cardioverter defibrillator patients with ischaemic heart disease: the FADES risk score

“…Nonetheless, in the majority of patients, indication for an ICD was made in the presence of a depressed left ventricular ejection fraction (LVEF) with or without non-sustained ventricular tachycardia 5 12. Ischaemic heart disease was defined as the presence of significant coronary artery disease (a diameter stenosis of at least 50% in at least one coronary artery) 14 15. Exclusion criteria for the current analysis consisted of congenital structural or monogenetic heart disease.…”

Chronic total occlusion in an infarct‐related coronary artery and the risk of appropriate ICD therapies

“…On the other hand, especially among secondary prevention ICD candidates, the identification of high‐risk subgroups may help optimizing the therapeutic strategy, including ventricular tachycardia (VT) ablation. Unfortunately, previous studies regarding predictors of appropriate ICD therapies in secondary prevention patients have come to inhomogeneous results …”