Recurrence rates of primary basal cell carcinoma in facial risk areas treated with curettage and electrodesiccation

Rodríguez-Vigil, Tomás; Vázquez‐López, Francisco; Pérez‐Oliva, Narciso

doi:10.1016/j.jaad.2006.07.007

Cited by 94 publications

(71 citation statements)

References 25 publications

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“…Some surgeons still argue in favor of SE or electrodesiccation [14] of facial skin cancers. The limitations of this technique are well documented.…”

Section: Discussionmentioning

confidence: 99%

Surgical Excision of Basal Cell Carcinoma with Complete Margin Control: Outcome at 5-Year Follow-Up

et al. 2010

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Background: The incidence of skin cancer and especially basal cell carcinoma (BCC) has increased in the last few decades. The gold standard of care is usually a surgical excision, but it also has the risk of local recurrence depending on tumor characteristics. Objectives: We analyzed the 5-year cure rates after surgical excision of BCC with complete margin control using paraffin-embedded sections. Methods: A retrospective analysis of 671 patients (45.3% male, 54.7% female) with 777 primary and 85 with recurrent BCC were collected during 2001–2003. All patients underwent surgery with complete margin control using paraffin-embedded sections. When the histological examination revealed a positive margin, another surgical step was performed in the area of residual tumor. Results: Five-year follow-up examinations were possible in 630/862 (73.1%) of patients with BCC. In the group with primary BCC (n = 562), 3 tumor recurrences (0.5%) were identified; in the group with recurrent BCC (n = 68), 2 tumor recurrences (2.9%) were seen, resulting in an overall 5-year recurrence rate of 0.8% for all patients with BCC. The mean tumor recurrence time after surgery was 36.6 months. Conclusion: Local complete tumor resection confirmed by complete margin control using paraffin-embedded sections can achieve excellent cure rates for both primary and recurrent BCC.

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“…Some surgeons still argue in favor of SE or electrodesiccation [14] of facial skin cancers. The limitations of this technique are well documented.…”

Section: Discussionmentioning

confidence: 99%

Surgical Excision of Basal Cell Carcinoma with Complete Margin Control: Outcome at 5-Year Follow-Up

et al. 2010

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“…58,59 Moreover, C&E may be associated with a longer healing time and inferior cosmetic outcome compared with standard excision, and it is best avoided in cosmetically sensitive areas. 44 …”

Section: Curretage and Electrodessicationmentioning

confidence: 99%

Guidelines of care for the management of basal cell carcinoma

Baum¹,

Bordeaux²,

Brown³

et al. 2018

Journal of the American Academy of Dermatology

326

219

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Basal cell carcinoma (BCC) is the most common form of human cancer, with a continually increasing annual incidence in the United States. When diagnosed early, the majority of BCCs are readily treated with office-based therapy, which is highly curative. In these evidence-based guidelines of care, we provide recommendations for the management of patients with BCC, as well as an in-depth review of the best available literature in support of these recommendations. We discuss biopsy techniques for a clinically suspicious lesion and offer recommendations for the histopathologic interpretation of BCC. In the absence of a formal staging system, the best available stratification based on risk for recurrence is reviewed. With regard to treatment, we provide recommendations on treatment modalities along a broad therapeutic spectrum, ranging from topical agents and superficially destructive modalities to surgical techniques and systemic therapy. Finally, we review the available literature and provide recommendations on prevention and the most appropriate follow-up for patients in whom BCC has been diagnosed. ( J Am Acad Dermatol

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“…[162][163][164] The recurrent tumor has a worse prognosis because the relationship between the tumor and its stroma may be altered as a result of treatment primarily established, facilitating its dissemination. It may show exulcerations, 154 more evident cellular dysplasia, loosening of the tumor cell cords, stromal fibrosis and reduction of peritumoral inflammatory reaction, increasing the spread of cancer cells.…”

Section: Prognosismentioning

confidence: 99%

Epidemiologia do carcinoma basocelular

Chinem

Miot

2011

An. Bras. Dermatol.

124

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Basal cell carcinoma is the most common malignant neoplasm in humans and its incidence has increased over the last decades. Its high frequency significantly burdens the health system, making the disease a public health issue. Despite the low mortality rates and the rare occurrence of metastases, the tumor may be locally invasive and relapse after treatment, causing significant morbidity. Exposure to ultraviolet radiation is the main environmental risk factor associated with its cause. However, other elements of risk are described, such as light skin phototypes, advanced age, family history of skin carcinoma, light eyes and blond hair, freckles in childhood and immunosuppression. Behavioral aspects such as occupational sun exposure, rural labor and sunburns at a young age also play a role. Between 30% and 75% of the sporadic cases are associated with patched hedgehog gene mutation, but other genetic changes are also described. The tumor is commonly found in concomitance with skin lesions related to chronic sun exposure, such as actinic keratoses, solar lentigines and facial telangiectasia. The prevention of basal cell carcinoma is based on the knowledge of risk factors, early diagnosis and treatment, as well as on the adoption of specific measures, particularly in susceptible populations. The authors present a review of the epidemiology of basal cell carcinoma. Keywords: Injections, intradermal; Review; Skin; Therapeutics Resumo: O carcinoma basocelular é a neoplasia maligna mais comum em humanos e sua incidência vem aumentando nas últimas décadas. Sua grande frequência gera significativo ônus ao sistema de saúde, configurando problema de saúde pública. Apesar das baixas taxas de mortalidade e de rara ocorrência de metástases, o tumor pode apresentar comportamento invasivo local e recidivas após o tratamento, provocando importante morbidade. Exposição à radiação ultravioleta representa o principal fator de risco ambiental associado a sua gênese. Entretanto, descrevem-se outros elementos de risco: fotótipos claros, idade avançada, história familiar de carcinomas de pele, olhos e cabelos claros, sardas na infância e imunossupressão, além de aspectos comportamentais, como exercício profissional exposto ao sol, atividade rural e queimaduras solares na juventude. Entre 30% e 75% dos casos esporádicos estão associados à mutação do gene patched hedgehog, mas outras alterações genéticas são ainda descritas. A neoplasia é comumente encontrada concomitantemente com lesões cutâneas relacionadas à exposição solar crônica, tais como: queratoses actínicas, lentigos solares e telangiectasias faciais. A prevenção do carcinoma basocelular se baseia no conhecimento de fatores de risco, no diagnóstico e tratamento precoces e na adoção de medidas específicas, principalmente, nas populações susceptíveis. Os autores apresentam uma revisão da epidemiologia do carcinoma basocelular.

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Recurrence rates of primary basal cell carcinoma in facial risk areas treated with curettage and electrodesiccation

Cited by 94 publications

References 25 publications

Surgical Excision of Basal Cell Carcinoma with Complete Margin Control: Outcome at 5-Year Follow-Up

Surgical Excision of Basal Cell Carcinoma with Complete Margin Control: Outcome at 5-Year Follow-Up

Guidelines of care for the management of basal cell carcinoma

Epidemiologia do carcinoma basocelular

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