2001
DOI: 10.1080/080352501750258702
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Recurrent abdominal and flank pain in children with idiopathic hypercalciuria

Abstract: We describe 52 children with RAP or back pain due to IH and recommend that IH be considered in the differential diagnosis of RAP in childhood.

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Cited by 4 publications
(7 citation statements)
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“…However, in a previous publication, we reported that 37% of children diagnosed by our group with urinary stones of various metabolic etiologies had no calculi detected with ultrasonography performed 2-28 months prior [8]. It has been hypothesized [9] that microcrystallization with injury to the urinary tract epithelium is the etiology of these non-calculi disorders. Moreover, the limited sensitivity of ultrasonography and X-ray plain film [10] may contribute to the delayed diagnosis of occult urolithiasis.…”
Section: Introductionmentioning
confidence: 59%
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“…However, in a previous publication, we reported that 37% of children diagnosed by our group with urinary stones of various metabolic etiologies had no calculi detected with ultrasonography performed 2-28 months prior [8]. It has been hypothesized [9] that microcrystallization with injury to the urinary tract epithelium is the etiology of these non-calculi disorders. Moreover, the limited sensitivity of ultrasonography and X-ray plain film [10] may contribute to the delayed diagnosis of occult urolithiasis.…”
Section: Introductionmentioning
confidence: 59%
“…The finding of an abnormality in urinary solute excretion, however, does not indicate per se a cause-effect relationship with symptoms as illustrated by hypercalciuria, which is not uncommon in otherwise healthy asymptomatic children [11]. Improvement or resolution of symptoms after therapy has been recorded in some children with hypercalciuria and no detectable stones [9][10][11][12]. However, due to the limited sample of these studies [9][10][11][12] and to the marked variability in the recurrence of symptoms in childhood idiopathic hypercalciuria and hyperuricosuria [5,6], a cause-effect relationship between occult urolithiasis and symptoms has not yet been clearly demonstrated.…”
Section: Introductionmentioning
confidence: 93%
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“…A majority of them responded to the therapy, but five failed to improve with the said therapy. The authors speculated that calcium crystals caused irritation to the urinary tract epithelium, and that the actual pain may be related to pelviureteral and bladder spasms, a result of the crystal injury, since antispasmodics often improve without a thiazide treatment [14].…”
Section: Discussionmentioning
confidence: 99%
“…Also, hypercalciuria can cause recurrent abdominal pain, dysuria, pollakuria, urgency and nocturnal enuresis [1,2,3]. Calcium measurement in 24-h collected urine is essential for the diagnosis of hypercalciuria.…”
Section: Introductionmentioning
confidence: 99%