Recurrent Abdominal Pain and Dietary Fiber

Christensen, Mogens Fjord

doi:10.1001/archpedi.1986.02140220020009

Cited by 28 publications

(27 citation statements)

References 5 publications

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“…Sample sizes ranged from 21 to 200, and follow-up varied from 2 weeks to 5 years. Four trials investigated fiber supplements compared with placebo, 24,[36][37][38] and 2 trials studied a lactose-free diet. 39,40 Four trials investigated probiotics, 27,41-43 and 3 trials compared HT versus standard care or a wait-list.…”

Section: Resultsmentioning

confidence: 99%

“…25,31,32,38,42,44,47,49,50 Four studies assessed quality of life, 25,28,29,44 and 8 studies assessed adverse effects. 24,25,37,38,[41][42][43][44] Data of 3 studies were pooled to perform a meta-analysis of the efficacy of fiber supplements, [36][37][38] and 3 studies were used to perform a meta-analysis on probiotics. [41][42][43] Table 1 presents the characteristics of the included studies.…”

Section: Resultsmentioning

confidence: 99%

“…36,[44][45][46]48,49 Due to the nature of HT, CBT, WSD, and yoga, blinding was not possible for the caregiver or patient. 25,28,29,31,32,[44][45][46][47][48][49][50] Dropout was considerable in 4 studies 36,40,41,47 or vaguely described in 3 others. 31,46,50 Two studies excluded patients due to poor compliance.…”

Section: Methodologic Qualitymentioning

confidence: 99%

“…Two systematic reviews 15 36,37 Children received fiber supplements for 6 weeks. No information was available regarding daily fiber intake before and/or during intervention weeks.…”

Section: Fiber Supplementsmentioning

confidence: 99%

“…56 However, studies in children and adolescents evaluating ispaghula husk and glucomannan found no favorable effects. 36,38 Improvement in abdominal pain frequency was reported after administration of corn fiber, 37 but questions were raised whether the statistical analyses were adequate. Re-analyses by HuertasCeballos et al 15 failed to replicate the findings.…”

Section: Alternative Medicinementioning

confidence: 99%

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Nonpharmacologic Treatment of Functional Abdominal Pain Disorders: A Systematic Review

et al. 2015

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BACKGROUND AND OBJECTIVE: Various nonpharmacologic treatments are available for pediatric abdominal pain-related functional gastrointestinal disorders (AP-FGIDs). Data on efficacy and safety are scarce. The goal of this study was to summarize the evidence regarding nonpharmacologic interventions for pediatric AP-FGIDs: lifestyle interventions, dietary interventions, behavioral interventions, prebiotics and probiotics, and alternative medicine.METHODS: Searches were conducted of the Medline and Cochrane Library databases. Systematic reviews and randomized controlled trials (RCTs) concerning nonpharmacologic therapies in children (aged 3-18 years) with AP-FGIDs were included, and data were extracted on participants, interventions, and outcomes. The quality of evidence was assessed by using the GRADE approach.RESULTS: Twenty-four RCTs were found that included 1390 children. Significant improvement of abdominal pain was reported after hypnotherapy compared with standard care/wait-list approaches and after cognitive behavioral therapy compared with a variety of control treatments/wait-list approaches. Written self-disclosure improved pain frequency at the 6-month follow-up only. Compared with placebo, Lactobacillus rhamnosus GG (LGG) and VSL#3 were associated with significantly more treatment responders (LGG relative risk: 1.31 [95% confidence interval: 1.08 to 1.59]; VSL#3: P , .05). Guar gum significantly improved irritable bowel syndrome symptom frequency; however, no effect was found for other fiber supplements (relative risk: 1.17 [95% confidence interval: 0.75 to 1.81]) or a lactose-free diet. Functional disability was not significantly decreased after yoga compared with a wait-list approach. No studies were found concerning lifestyle interventions; gluten-, histamine-, or carbonic acid-free diets; fluid intake; or prebiotics. No serious adverse effects were reported. The quality of evidence was found to be very low to moderate. CONCLUSIONS:Although high-quality studies are lacking, some evidence shows efficacy of hypnotherapy, cognitive behavioral therapy, and probiotics (LGG and VSL#3) in pediatric AP-FGIDs. Data on fiber supplements are inconclusive.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodologic Qualitymentioning

confidence: 99%

“…Two systematic reviews 15 36,37 Children received fiber supplements for 6 weeks. No information was available regarding daily fiber intake before and/or during intervention weeks.…”

Section: Fiber Supplementsmentioning

confidence: 99%