Recurrent and pre-eruptive acute cerebellar ataxia: A rare case of varicella

Preeruptive Unilateral Cerebellar Ataxia in an Immunocompetent Adult: A Rare Case of Varicella

“…All the published reports described the phenomenon in childhood, and it is noteworthy that almost all were male patients. The interval between the onset of cerebellar ataxia and development of rash was variable, up to 19 days as reported by Takeuchi et al [10] Our present patient represented the most unusual one, occurring in adulthood, female, and had the longest preeruptive phase of 28 days. Interestingly to date, there are four recognized cases of virologically confirmed VZV cerebellitis without skin manifestation in adult.…”

“…It is postulated that the preeruptive neurological symptoms are due to direct viral invasion of the central nervous system, whereas the symptoms occurring after the eruptive phase may be the result of postinfectious autoimmune process. [9,10,12] The unilateral clinical presentation of the case showed that the pathology is not always bilateral.…”

“…Takeuchi et al [10] 1987 2 Male 19 5 Liu and Urion [11] 1992 2 Male 16 6 Dangond et al [12] 1993 4 Female 5 7…”

Postvaricella multiaxial nervous system involvement in an immunocompetent adult female: an unusual presentation

“…The child had multiple ischaemic infarcts on MRI. Takeuchi et al [7] reported recurrent and pre-eruptive acute cerebellar ataxia likely due to direct invasion by varicella-zoster. The literature is replete with cases of cerebellitis and encephalitis after chickenpox.…”