Recurrent Epididymo-Orchitis in Patients With Behçet’s Disease

Abstract

Epididymo-orchitis in patients with Behçet's disease is not as infrequent as believed. It was not the first manifestation of the disease but developed during followup. In any patient with epididymo-orchitis Behçet's disease should be considered, particularly in regions with a high prevalence of the disease.

Acute epididymitis

“…The anti‐arrhythmic drug amiodarone can rarely provoke a reversible sterile epididymitis [47]. Other rare noninfective causes include vasculitis; epididymitis has been reported in patients with polyarteritis nodosa, Behçet's disease and Henoch‐Schonlein purpura [48–50]. A proportion of cases of acute epididymitis remains idiopathic.…”

Serial Ultrasonography Assessments of a Testicular Infarction Mimicking Testicular Tumor in a Behcet Disease Patient

“…The incidence of epididymo-orchitis was 31% in Iraqi but only 6% in Turkish patients. 4 Zouboulis et al 5 reported prostatitis and epididymo-orchitis with BD in 22% of cases.…”

“…Infection has also been implicated; however, urinary cultures have consistently been negative in case series, and inflammation subsides with administration of anti-inflammatory drugs. 4 , 6 Clinical presentation in different case series and reports was mainly as testicular pain, with testicular mass being less common. 7 , 8 , 9 , 10 …”

Recurrent epididymo-orchitis in an 8-year-old child with Kostmann syndrome (severe congenital neutropenia)

“…Inflammatory processes of the testes, especially viral orchitis, trauma or side-effects of medication, such as amiodaron and some vasculopathies, need to be excluded. 6,7 In cases of recurrent EO, infectious causes such as brucella and tuberculosis must be considered. 8,9 In this case, presumably the acute and recurrent EO was caused by systemic infection associated with neutropenia.…”