Recurrent GBS With COVID-19 in a Child: A Case Report

Akçay, Nihal; Oğur, Mustafa; Menentoğlu, Mehmet Emin; Sofuoğlu, Ayşe İrem; Işik, İlhan; Şevketoğlu, Esra

doi:10.1097/inf.0000000000003809

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…However, these two factors were also general risk factors for COVID-19 [ 60 ] and mortality due to this disease [ 61 ]. Nonetheless, cases of GBS associated with COVID-19 in children have also been described [ 59 , 62 , 63 , 64 , 65 ].…”

Section: Covid-19 and Guillain–barre Associationmentioning

confidence: 99%

The Impact of COVID-19 on the Guillain–Barré Syndrome Incidence

Kopańko,

Zabłudowska,

Zajkowska

et al. 2024

Biomedicines

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Despite the fact that the global COVID-19 pandemic has officially ended, we continue to feel its effects and discover new correlations between SARS-CoV-2 infection and changes in the organism that have occurred in patients. It has been shown that the disease can be associated with a variety of complications, including disorders of the nervous system such as a characteristic loss of smell and taste, as well as less commonly reported incidents such as cranial polyneuropathy or neuromuscular disorders. Nervous system diseases that are suspected to be related to COVID-19 include Guillain–Barré syndrome, which is frequently caused by viruses. During the course of the disease, autoimmunity destroys peripheral nerves, which despite its rare occurrence, can lead to serious consequences, such as symmetrical muscle weakness and deep reflexes, or even their complete abolition. Since the beginning of the pandemic, case reports suggesting a relationship between these two disease entities have been published, and in some countries, the increasing number of Guillain–Barré syndrome cases have also been reported. This suggests that previous contact with SARS-CoV-2 may have had an impact on their occurrence. This article is a review and summary of the literature that raises awareness of the neurological symptoms’ prevalence, including Guillain–Barré syndrome, which may be impacted by the commonly occurring COVID-19 disease or vaccination against it. The aim of this review was to better understand the mechanisms of the virus’s action on the nervous system, allowing for better detection and the prevention of its complications.

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Section: Covid-19 and Guillain–barre Associationmentioning

confidence: 99%

The Impact of COVID-19 on the Guillain–Barré Syndrome Incidence

Kopańko,

Zabłudowska,

Zajkowska

et al. 2024

Biomedicines

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Intrinsic Factors Behind the Long‐COVID: V. Immunometabolic Disorders

Adilović,

Hromić‐Jahjefendić,

Mahmutović

et al. 2024

J of Cellular Biochemistry

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The complex link between COVID‐19 and immunometabolic diseases demonstrates the important interaction between metabolic dysfunction and immunological response during viral infections. Severe COVID‐19, defined by a hyperinflammatory state, is greatly impacted by underlying chronic illnesses aggravating the cytokine storm caused by increased levels of Pro‐inflammatory cytokines. Metabolic reprogramming, including increased glycolysis and altered mitochondrial function, promotes viral replication and stimulates inflammatory cytokine production, contributing to illness severity. Mitochondrial metabolism abnormalities, strongly linked to various systemic illnesses, worsen metabolic dysfunction during and after the pandemic, increasing cardiovascular consequences. Long COVID‐19, defined by chronic inflammation and immune dysregulation, poses continuous problems, highlighting the need for comprehensive therapy solutions that address both immunological and metabolic aspects. Understanding these relationships shows promise for effectively managing COVID‐19 and its long‐term repercussions, which is the focus of this review paper.

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