Recurrent Intraepithelial Neoplasia Treatment

Confocal biomicroscopy of corneal intraepithelial neoplasia regression following interferon alpha 2b treatment

“…Under this regimen, healing was observed within 3 months. IFN2B was well tolerated, with only localised and mild conjunctival hyperaemia being observed 2. No recurrence was detectable more than 2 years following IFN2B treatment.…”

Conjunctival Intraepithelial Neoplasia – Clinical Presentation, Diagnosis and Treatment Possibilities

“…In general, it seems that the disadvantage with topical treatment is the long duration. We must emphasize the importance of long term follow-up for CIN patients because recurrences can occur anywhere from 33 days to 11.5 years (Tabin et al, 1997), although most recurrent CIN occurs within 2 years of initial excision (Schechter et al, 2005).…”