Recurrent oesophageal cancer complicated by tracheo-oesophageal fistula: improved palliation by means of parallel tracheal and oesophageal stenting

Schweigert, Michael; Posada-González, María; Dubecz, Attila; Öfner, Dietmar; Muschweck, Herbert; Stein, Hubert J.

doi:10.1093/icvts/ivt466

Cited by 16 publications

(7 citation statements)

References 22 publications

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“…Alternatively, polymer materials are best when good flexibility and high tensile strength are desired properties. The treatment of an esophageal stricture, esophageal fistula, and postoperative anastomotic fistula is prevalent in literature [ 11 , 12 , 13 , 14 , 15 ]. Combining the two previously mentioned types of treatments, currently existing stents consist of a polymer membrane coating on a metal stent.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of a Delaying Biodegradable Magnesium Alloy-Based Esophageal Stent via Coating Elastic Polymer

Yuan

Cao

et al. 2016

Materials

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Esophageal stent implantation can relieve esophageal stenosis and obstructions in benign esophageal strictures, and magnesium alloy stents are a good candidate because of biodegradation and biological safety. However, biodegradable esophageal stents show a poor corrosion resistance and a quick loss of mechanical support in vivo. In this study, we chose the elastic and biodegradable mixed polymer of Poly(ε-caprolactone) (PCL) and poly(trimethylene carbonate) (PTMC) as the coated membrane on magnesium alloy stents for fabricating a fully biodegradable esophageal stent, which showed an ability to delay the degradation time and maintain mechanical performance in the long term. After 48 repeated compressions, the mechanical testing demonstrated that the PCL-PTMC-coated magnesium stents possess good flexibility and elasticity, and could provide enough support against lesion compression when used in vivo. According to the in vitro degradation evaluation, the PCL-PTMC membrane coated on magnesium was a good material combination for biodegradable stents. During the in vivo evaluation, the proliferation of the smooth muscle cells showed no signs of cell toxicity. Histological examination revealed the inflammation scores at four weeks in the magnesium-(PCL-PTMC) stent group were similar to those in the control group (p > 0.05). The α-smooth muscle actin layer in the media was thinner in the magnesium-(PCL-PTMC) stent group than in the control group (p < 0.05). Both the epithelial and smooth muscle cell layers were significantly thinner in the magnesium-(PCL-PTMC) stent group than in the control group. The stent insertion was feasible and provided reliable support for at least four weeks, without causing severe injury or collagen deposition. Thus, this stent provides a new stent for the treatment of benign esophageal stricture and a novel research path in the development of temporary stents in other cases of benign stricture.

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Section: Introductionmentioning

confidence: 99%

Fabrication of a Delaying Biodegradable Magnesium Alloy-Based Esophageal Stent via Coating Elastic Polymer

Yuan

Cao

et al. 2016

Materials

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“…SEMS insertion effectively closes fistulas in 88.9-96% of patients [4, 6, 9−12]. In selected cases, endoscopic double stenting (airway and esophageal) is performed [13,14]. However, SEMS implantation could lead to complications, which occur in 10−30% of cases [4,7,12].…”

Section: Introductionmentioning

confidence: 99%

“…SEMS implantation improves the quality of life and increases the lifespan [6,11,12]. The successful stent placement enables the patient to receive palliative chemo-or radiotherapy [13].…”

Section: Introductionmentioning

confidence: 99%

Self-Expandable Metallic Stents in Oesophago-Respiratory Fistulas Treatment in Neoplasms—Case Reports and Literature Review

Marczyński¹,

Pajak²,

Komandowska³

et al. 2015

Advances in Respiratory Medicine

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Self-expandable metallic stents (SEMS) insertion to the oesophagus is the method of choice in palliative treatment of malignant oesophago-respiratory fistulas (ERF). ERF evolve as a result of 0.2−5% of advanced oesopghageal or lung cancer. They also appear after radiotherapy. EFR are serious and lethal complications. SEMS insertion is an effective, safe, technically simple and minimally invasive solution. Potential complications of SEMS include thoracic pain, bleeding, perforation, stent migration, tumour overgrowth or ingrowth and food bolus impaction. The article presents three cases of patients with advanced lung cancer with EFR subjected to SEMS insertion procedure in our centre.

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“…Эта ситуация может возникнуть вместе с дисфагией, раньше ее или спустя некоторое время после установки стента в пищевод, что вызовет необходимость установки стента в трахею. В зарубежной литературе подобные ситуации описываются достаточно часто [4][5][6][7][10][11][12][13][14][15]. При анализе публикаций в отечественной литературе нам не встретились подобные публикации.…”

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“…Эндоскопические вмешательства такого рода направлены на улучшение качества жизни пациента, возможность проведения дополнительных методов лечения. Технически они не сложны, имеют минимальное число осложнений и эффективно купируют дисфагию и дыхательную недостаточность [1,3,6,9,11,14,15].…”

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Tracheo-Esophageal Stenting in Their Tumor Stenosis

Drobyazgin

Chikinev

Судовых

et al. 2016

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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The article presents the results of diagnostics and treatment of 6 patients, whom the trachea-esophageal stenting was performed (5 men, 1 woman). The age of patients was from 49 to 78 years old. The indication to stent implantation was in cases of esophageal cancer in 4 patients. Metastatic lesions of the lymph nodes of the mediastinum was the reason of esophageal stenosis after previously performed surgery (type of Lewes operation) in one case. Another reason of surgery was central cancer of the right lung with invasion to the mediastinum, trachea and esophagus compression in one patient. Treatment management was determined by presence of respiratory failure and dysphagia evidence. The trachea stenting was carried out as the first stage of treatment in case of respiratory failure. The esophageal stenting was made in case of dysphagia. There weren’t any complications. The trachea-esophageal patency was restored.

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Recurrent oesophageal cancer complicated by tracheo-oesophageal fistula: improved palliation by means of parallel tracheal and oesophageal stenting

Cited by 16 publications

References 22 publications

Fabrication of a Delaying Biodegradable Magnesium Alloy-Based Esophageal Stent via Coating Elastic Polymer

Fabrication of a Delaying Biodegradable Magnesium Alloy-Based Esophageal Stent via Coating Elastic Polymer

Self-Expandable Metallic Stents in Oesophago-Respiratory Fistulas Treatment in Neoplasms—Case Reports and Literature Review

Tracheo-Esophageal Stenting in Their Tumor Stenosis

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