Pityriasis rosea is a self-limiting acute exanthem of unkown causes. Pityriasis rosea is known to recur in some patients. In two retrospective studies involving large case series, the frequency of recurrence was reported as 3.7% and 2.8%. Between the years of 2013-2017, 212 patients admitted to the dermatology outpatient clinic of Istanbul Medipol University were included in the study. In the current prospective study, we found this rate to be 25.9%. It is considered that the rate of pityriasis rosea recurrence is actually greater than reported in the literature. Pityriasis rosea is a common acute exanthema of un known aetiology, which causes severe anxiety. In this study, the demographic data of pityriasis rosea pa tients, who presented to our clinic between 2013 and 2017, were prospectively recorded. The patients with a confirmed pityriasis rosea diagnosis were followed up for 4 years in order to investigate the recurrence rate. Of the clinically suspected patients, having a typi cal history of pityriasis rosea manifestations, a herald patch, and/or secondary coloured squamous lesions, 400 were confirmed by biopsy to have pityriasis rosea. The 4year followup was completed in 212 patients, of whom 136 (64.2%) were female and 76 (35.8%) were male. The recurrence rate was determined as 25.9% at the end of the 4year followup period.