“…The association between cholangiocarcinoma and RPC is well recognized, and the incidence of cholangiocarcinoma in patients with hepatolithiasis at the time of hepatic resection ranges from 2.4% to 23.3%. 18,21,23,[29][30][31][32] None of the patients in the present series had cholangiocarcinoma at the time of primary surgery. Only one patient developed cholangiocarcinoma in the follow up period.…”
“…The association between cholangiocarcinoma and RPC is well recognized, and the incidence of cholangiocarcinoma in patients with hepatolithiasis at the time of hepatic resection ranges from 2.4% to 23.3%. 18,21,23,[29][30][31][32] None of the patients in the present series had cholangiocarcinoma at the time of primary surgery. Only one patient developed cholangiocarcinoma in the follow up period.…”
“…8 In the West, this disease has become increasingly more prevalent in centers that receive immigrants from endemic regions. Harris et al 4 describe a doubling of RPC patients presenting to their center in San Francisco during 1984-1995 relative to 1970-1983. Our own experience is similar.…”
Surgery is a valuable part of multidisciplinary management of recurrent pyogenic cholangitis with hepatolithiasis. Hepatectomy is a useful option for selected cases. Hutson loops are useful in some cases for managing stone recurrence. Cholangiocarcinoma risk is elevated in this disease.
“…The clinical presentation of recurrent pyogenic cholangitis is often an initial episode of cholangitis in 15-33 % of cases [81]. Fever or sepsis may result from cholangitis, abscess formation, or pylephlebitis.…”
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