Bulimia nervosa, a mental illness 4 times more common than anorexia nervosa, is characterized by binge-eating followed by compensatory purging behaviors, which include self-induced vomiting, diuretic abuse, laxative abuse, and misuse of insulin. Patients with bulimia nervosa are at risk of developing medical complications that affect all body systems, especially the renal and electrolyte systems. Behavior cessation can reverse some, but not all, medical complications.
KEY POINTSMost people with bulimia nervosa are young and of normal weight, or even overweight, making detection and diagnosis diffi cult.As a consequence of purging behaviors, pseudo-Bartter syndrome can develop due to chronic dehydration, placing patients at risk for electrolyte abnormalities such as hypokalemia, as well as marked and rapid edema formation when purging is interrupted.Electrolyte and metabolic disturbances are the most common causes of morbidity and mortality in patients with bulimia nervosa. Hypokalemia should be managed aggressively to prevent electrocardiographic changes and arrhythmias such as torsades de pointes.Diabetic patients who purge calories through manipulation of their blood glucose are at high risk for hyperglycemia, ketoacidosis, and premature microvascular complications.Gastrointestinal complaints are common and include gastroesophageal refl ux disease.