Recurrent Takotsubo Cardiomyopathy: An Opportunity to Clarify Causation and Prognosis

Angelini, Paolo

doi:10.14503/thij-18-6778

Cited by 10 publications

(11 citation statements)

References 8 publications

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“…Emotional and physical stressors are a common denominator, and perhaps a paradigm shift in risk factor modification should be implanted upon discharge. Approximately 29% of SCAD and 2-10% of TTS cases have the risk of recurrence [19][20][21]. These statistics might underestimate the true number of cases because these conditions continue to remain misdiagnosed or underdiagnosed.…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics and outcomes of patients with takotsubo syndrome versus spontaneous coronary artery dissection

et al. 2023

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Section: Discussionmentioning

confidence: 99%

Clinical characteristics and outcomes of patients with takotsubo syndrome versus spontaneous coronary artery dissection

et al. 2023

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“…In our own experience, those rare patients who have a positive Ach test more than 1 week after a TTS episode have a high rate of TTS recurrence (or of Prinzmetal angina) [10,18].…”

Section: What Is Transient Takotsubo Cardiomyopathy?mentioning

confidence: 83%

“…TTS resolves spontaneously and completely over a few days in 90% of cases [6][7][8][9], and mostly it occurs only once in a person's lifetime (enabling what seems a sort of "automatic vaccination," rarely previously observed in medicine) [10].…”

Section: What Is Transient Takotsubo Cardiomyopathy?mentioning

confidence: 99%

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Opportunities and Limitations in the Study of Transient Takotsubo Syndrome in Animal Models

Angelini¹,

Gamero

2020

J Clin Med Res

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“…The characteristics of ECG are affected by the region of left ventricular ballooning, time from symptom onset, degree of myocardial edema and recovery rate of cardiomyocytes. T waves may be inverted when the sinus rhythm is restored in patients with pacemakers[ 11 - 13 ]. Therefore, cardiac troponin elevation is helpful for the diagnosis of TCM.…”

Section: Discussionmentioning

confidence: 99%

Recurrent Takotsubo cardiomyopathy triggered by emotionally stressful events: A case report

Wu¹,

Cheng²,

Liu³

et al. 2021

WJCC

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BACKGROUND Takotsubo cardiomyopathy (TCM) is characterized by reversible left ventricular dysfunction triggered by emotional or physical stress. Only 1%-2% of patients with acute coronary syndrome are diagnosed with TCM. Although obstructive coronary artery disease is frequently considered to be the cause of chest pain, TCM should be considered in some clinical settings. In this case, clinicians did not make a timely and accurate diagnosis for TCM due to a lack of knowledge until the third hospitalization with a left ventriculogram. CASE SUMMARY A 55-year-old postmenopausal woman had intermittent chest pain following emotionally stressful events three times in the past 3 years. Cardiac troponin levels increased after each instance of symptom onset. A transthoracic echocardiogram showed reversible left ventricular dysfunction. The patient underwent three coronary angiograms without evidence of coronary artery disease. A left ventriculogram was first performed at the third hospitalization and revealed apical akinesia with ballooning of the apical region and consistent hypercontractile basal segments. The diagnosis of TCM was confirmed. The patient was treated with an angiotensin-converting-enzyme inhibitor (perindopril) and a β-blocker (metoprolol). No complications occurred during the patient’s hospitalization. The patient was told to avoid stressful events. During the 9-mo follow-up visit, the patient was asymptomatic with an ejection fraction of 55%. CONCLUSION Clinicians should be conscious of the possibility of TCM, especially in postmenopausal women presenting with clinical manifestations similar to acute coronary syndrome without coronary occlusion.

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Recurrent Takotsubo Cardiomyopathy: An Opportunity to Clarify Causation and Prognosis

Cited by 10 publications

References 8 publications

Clinical characteristics and outcomes of patients with takotsubo syndrome versus spontaneous coronary artery dissection

Clinical characteristics and outcomes of patients with takotsubo syndrome versus spontaneous coronary artery dissection

Opportunities and Limitations in the Study of Transient Takotsubo Syndrome in Animal Models

Recurrent Takotsubo cardiomyopathy triggered by emotionally stressful events: A case report

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