Recurrent Uveitis

Association of acute leptospirosis with systemic disease and uveitis in horses

“…Leptospirosis has long been associated with development of equine recurrent uveitis, a disease syndrome characterised by multiple recurrent episodes of uveitis separated by periods of quiescence of inflammation Verma et al 2010;Gerding and Gilger 2016;Gilger 2016). The horse in this report (Delph et al 2018) had severe bilateral uveitis, but by definition, it did not have ERU; but instead it had developed acute onset uveitis of only 5 days' duration.…”

Results of 654 trans-pars plana vitrectomies of equine eyes with recurrent uveitis – follow-up until 18 years after surgery

“…This includes, among other things, breed predisposition in horses with leopard-coat colour (Angelos et al 1988, Dwyer et al 1995, Kulbrock et al 2013, Baumgart 2014, Baumgart and Gerhards 2014) and an increased risk for Warmbloods with the specific MHC class I haplotype ELA-A9 (Deeg et al 2004). Other authors consider ERU as an autoimmune-mediated disease caused by any agent (Gilger et al 1999, Deeg et al 2001, Deeg et al 2002, Deeg et al 2004, Deeg et al 2006, Deeg 2008, Gilger et al 2008, Gilger 2010, 2015. Therefore, uveitis in horses belongs to a disease complex and can show variable symptoms and courses.…”

A review of investigated risk factors for developing equine recurrent uveitis

“…46,85,86 Viruses, such as the equine arteritis virus (EAV), influenza, and the equine herpes viruses (EHV-1, in particular) have been included as possible causes of uveitis for decades; however, few case reports or retrospective studies link ERU with viral infections. 8,87,88 Both EAV and influenza are reported to trigger conjunctivitis, periocular edema, and lacrimation, but further discussion of associated ocular pathology appears to be absent from the literature. [89][90][91][92][93] EHV-1, however, has been reported to infect ocular tissues and trigger uveitis.…”