Recurrent Vulvo-Vaginal Candidiasis: Diagnostic and Management Challenges in a Developing Country Context

Lema, Valentino M.

doi:10.15406/ogij.2017.07.00260

Cited by 14 publications

(24 citation statements)

References 76 publications

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“…The pH of the vaginal discharge is also an important indicator and normally stays within a range of 4.0–4.5. A pH above 4.7 is indicative of other infections such as bacterial vaginosis, trichomoniasis, or mixed infections [ 1 , 10 , 11 ]. For further differentiation between Candida species, additional culturing is needed, e.g., with chromogenic agar or Sabourad’s dextrose agar.…”

Section: Diagnosis Of Rvvcmentioning

confidence: 99%

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Treating (Recurrent) Vulvovaginal Candidiasis with Medical-Grade Honey—Concepts and Practical Considerations

Riel

Lardenoije

Oudhuis

et al. 2021

JoF

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Recurrent vulvovaginal candidiasis (RVVC) is a relapsing vaginal fungal infection caused by Candida species. The prevalence varies among age populations and can be as high as 9%. Treatment options are limited, and in 57% of the cases, relapses occur within six months after fluconazole maintenance therapy, which is the current standard of care. The pathogenesis of RVVC is multifactorial, and recent studies have demonstrated that the vaginal microenvironment and activity of the immune system have a strong influence on the disease. Medical-grade honey (MGH) has protective, antimicrobial, and immunomodulatory activity and forms a putative alternative treatment. Clinical trials have demonstrated that honey can benefit the treatment of bacterial and Candida-mediated vaginal infections. We postulate that MGH will actively fight ongoing infections; eradicate biofilms; and modulate the vaginal microenvironment by its anti-inflammatory, antioxidative, and immunomodulatory properties, and subsequently may decrease the number of relapses when compared to fluconazole. The MGH formulation L-Mesitran Soft has stronger antimicrobial activity against various Candida species than its raw honey. In advance of a planned randomized controlled clinical trial, we present the setup of a study comparing L-Mesitran Soft with fluconazole and its practical considerations.

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Section: Diagnosis Of Rvvcmentioning

confidence: 99%

“…This is especially relevant in the case of RVVC, in which non-albicans species (NAC) are becoming more prevalent. Similarly, susceptibility testing may be of adjuvant need in RVVC, as these infections are more resistant to antifungal agents [ 11 ].…”

Section: Diagnosis Of Rvvcmentioning

confidence: 99%

Treating (Recurrent) Vulvovaginal Candidiasis with Medical-Grade Honey—Concepts and Practical Considerations

Riel

Lardenoije

Oudhuis

et al. 2021

JoF

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“…Beberapa laporan menyatakan terdapat hubungan KVV dengan peningkatan transmisi dan penyebaran HIV. 4,5 Secara laboratoris, seorang wanita dikatakan memiliki gejala klinis kandidiasis vulvovaginal bila hitung jamur vagina lebih dari 103 CFU/ml dari cairan vagina. 3 Gejala secara umum adalah gatal, rasa terbakar, rasa sakit, vaginal discharge abnormal dan dispareunia.…”

Section: Kandidiasisunclassified

“…Pada vulva dapat terjadi eritema dengan fisura yang sering terlokalisasi pada tepi mukosa introitus vagina dan dapat meluas mengenai labia mayora disertai gatal dan kemerahan. 5 Candida albicans merupakan spesies penyebab yang sering ditemukan. Diagnosis kandidiasis vulvovaginal dapat dilakukan berdasarkan anamnesis, gejala klinis, diikuti dengan pemeriksaan mikroskopis menggunakan KOH 10%.…”

Section: Gejala Klinis Dan Penegakan Diagnosisunclassified

“…Hasil kultur berupa koloni berwarna putih, permukaan licin, menonjol disertai bau khas (yeast odor). 5,7,16 Berikut ini dapat dilihat salah satu gambaran spesies C.albicans sebagai penyebab terbanyak dari kandidiasis vulvovaginal : Gambar 1. C. albicans pada pulasan sediaan basah dari spesimen sekret vagina pasien candidiasis vagina.…”

Section: Gejala Klinis Dan Penegakan Diagnosisunclassified

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Aspek Klinis dan Diagnosis Kandidiasis Vulvovaginal

Harminarti¹

2021

JIK

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Candidiasis vulvovaginal is an infection of the vaginal and vulva area caused by yeast Candida. The most causative species is Candida albicans. This fungus is commensal in the vagina but it can become a pathogen, causing the infection under certain conditions. Several conditions can be risk factors for this infection. Women are mostly getting infections, especially of productive age. Complaints experienced cause disturbances in the form of itching accompanied by abnormal vaginal discharge. The clinician can make diagnostics based on anamnesis, clinical and microscopic examination. This paper provides information about the causes, risk factors, clinical symptoms, and laboratory testing.

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Limosilactobacillus reuteri 29A Cell-Free Supernatant Antibiofilm and Antagonistic Effects in Murine Model of Vulvovaginal Candidiasis

Boahen

Chew

Neela

et al. 2023

Probiotics & Antimicro. Prot.

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Recurrent Vulvo-Vaginal Candidiasis: Diagnostic and Management Challenges in a Developing Country Context

Cited by 14 publications

References 76 publications

Treating (Recurrent) Vulvovaginal Candidiasis with Medical-Grade Honey—Concepts and Practical Considerations

Treating (Recurrent) Vulvovaginal Candidiasis with Medical-Grade Honey—Concepts and Practical Considerations

Aspek Klinis dan Diagnosis Kandidiasis Vulvovaginal

Limosilactobacillus reuteri 29A Cell-Free Supernatant Antibiofilm and Antagonistic Effects in Murine Model of Vulvovaginal Candidiasis

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