Recursos hospitalarios y letalidad por infarto de miocardio. Estudio IBERICA

Álvarez-León, Eva E.; Elosúa, Roberto; Zamora, Alberto; Aldasoro, Elena; Galcerá, José; Vanaclocha, Hermelinda; Segura, Antonio; Fiol, Miquel; Turumbay, Javier; Pérez, Glória; Arteagoitia, José M.; Cabadés, Adolfo; Vega, Gema; Ayestarán, José I.; García, Vega; Hurtado-de-Saracho, Iraida; Navarro, Carmen; Zurriaga, Óscar; Muñiz, Javier; Sala, Joan; Marrugat, Jaume

doi:10.1016/s0300-8932(04)77142-0

Cited by 13 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cardiovascular risk is assessed mainly on the basis of classic risk factors, such as age, gender, smoking status, blood pressure, glucose levels, and lipid levels. However, studies have shown that at least 15% of patients with coronary artery disease (CAD) do not present classic risk factors, and some have poor prognosis 3,4 .…”

Section: Introductionmentioning

confidence: 99%

TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease

Duarte

Miranda

Cruz

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Members of the triggering receptor expressed on myeloid cells (TREM) family are associated with atherosclerosis risk and progression. TREML4 is upregulated in the early phase of acute coronary syndrome. We investigated the relationship between the mRNA expression of 13 genes in blood leukocytes, TREML4 polymorphisms, and coronary artery lesion extension (Friesinger index) in patients with coronary artery disease (CAD) (n = 137). TREML4 rs2803495 (A > G) and rs2803496 (T > C) variants and leukocyte mRNA expression were analysed by qRT-PCR. TREML4 expression was higher in patients with major coronary artery lesions than in subjects without or with low and intermediate lesions ( p < 0.05). However, TREML4 polymorphisms were not associated with coronary lesion extent. Presence of the rs2803495 G allele was not associated with increased TREML4 mRNA expression. Patients carrying the rs2803496 C allele (TC/CC genotypes) were more likely to express TREML4 mRNA than non-C allele carriers (allele C: OR 7.3, and 95% CI 1.9–27.5, p = 0.03). In conclusion, increased TREML4 mRNA expression in blood leukocytes is influenced by gene polymorphisms and is associated with more severe coronary artery lesions, suggesting its potential as a biomarker of the extent of coronary lesions in patients with CAD.

show abstract

Section: Introductionmentioning

confidence: 99%

TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease

Duarte

Miranda

Cruz

et al. 2019

Sci Rep

View full text Add to dashboard Cite

show abstract

Tendencias de la mortalidad por infarto agudo de miocardio y cambios en la esperanza de vida en Andalucía (1980-2014)

García-González

Grande

2018

Cardiocore

View full text Add to dashboard Cite

In-hospital Mortality Due to Acute Myocardial Infarction. Relevance of Type of Hospital and Care Provided. RECALCAR Study

Bertoméu

Cequier

Bernal

et al. 2013

Revista Española de Cardiología (English Edition)

Self Cite

View full text Add to dashboard Cite

The typology of the hospital, treatment in a cardiology unit, and percutaneous coronary intervention are significantly associated with the survival of a patient hospitalized for myocardial infarction. We recommend that the Spanish National Health Service establish health care networks that favor percutaneous coronary intervention and the participation of cardiology units in the management of patients with acute myocardial infarction.

show abstract

Recursos hospitalarios y letalidad por infarto de miocardio. Estudio IBERICA

Abstract: CCU admission is associated with a lower case fatality in the first 24 h. Admission to a basic hospital is associated with a higher 28-day case fatality even in patients who survive 24 h.

Cited by 13 publications

References 20 publications

TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease

TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease

Tendencias de la mortalidad por infarto agudo de miocardio y cambios en la esperanza de vida en Andalucía (1980-2014)

In-hospital Mortality Due to Acute Myocardial Infarction. Relevance of Type of Hospital and Care Provided. RECALCAR Study

Contact Info

Product

Resources

About