Recyclable Magnetic Copper Ferrite Nanoparticle Catalyzed One-pot Four-component Dakin-West Reaction: Efficient Synthesis of β-Acetamido Ketones

Two different facile and efficient approaches for the synthesis of various N-arylacetamides via N-acetylation of arylamines and straightforward one-pot reductive acetylation of nitroarenes promoted by recyclable CuFe2O4 nanoparticles in water

“…Furthermore, compared with iron oxides, spinel ferrites provide flexibility to control both crystal structures and magnetic properties by choosing different non-iron metals in spinel ferrite backbone and controlling their molar concentrations. Among various type of spinel ferrite magnetic nanoparticles (MNPs), CuFe 2 O 4 nanocomposite, in addition to numerous applications, has shown satisfactory performance as the recyclable catalyst in various organic transformations such as synthesis of heterocyclic compounds [46][47][48][49][50][51][52], Ullmann C-O coupling reaction [53], direct synthesis of chemical structures containing both phenol ester and benzothiazole moieties via dehydrogenative coupling reactions [54], reduction of p-nitrophenol [55], one-pot odorless carbon-sulfur bond formation reactions [56], directed phenol/formamide coupling [57], synthesis of diaryl/aryl alkyl sulfides via cross-coupling process [58], S-arylation of thioureas by aryl halides [59], one-pot four-component Dakin-West reaction (synthesis of β-acetamido ketones) [60], Friedel-Crafts acylation [61], N-arylation of heterocycles [62], direct C-H amination of benzothiazoles [63], oxidative hydroxylation of arylboronic acids [64], palm oil methanolysis [65], oxidation of benzyl alcohol [66], synthesis of unnatural arundines [67], N-arylation of indole and imidazole with aryl halide [68], and so on.…”