Recyclable palladium-catalyzed Suzuki coupling of aromatic triazine esters: A practical one-pot synthesis of aryl ketones from aromatic acids

Palladium-catalysed Suzuki–Miyaura coupling of α,β-unsaturated superactive triazine esters

“…19 Our group and others explored aryl acid triazine esters as an acylating reagent in Pd-catalysed C–C cross-coupling reactions. 20 Using triazine as a key element, we synthesized multifunctional phosphine ligands 21 and NHC ligands 22 for Pd-catalysed carbonylative coupling reactions. In light of triazine's unique ability to activate C acyl –O bonds and its catalytic implications, we envisioned superactive triazine esters of α,β-unsaturated carboxylic acids as potent acyl electrophiles for Pd catalysis.…”