Red Blood Cell Transfusion

West, F. Bernadette; Kelher, Marguerite; Silliman, Christopher C.

doi:10.1007/978-3-319-28308-1_19

Cited by 2 publications

(4 citation statements)

References 78 publications

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“…The National Inpatient Sample uses a stratified probability sample of 20% of all inpatient discharges (representing approximately 96% of the US population) . Analyses were weighted to account for the sampling design and generate nationally representative estimates.…”

Section: Methodsmentioning

confidence: 99%

“…Methods | The National Inpatient Sample uses a stratified probability sample of 20% of all inpatient discharges (representing approximately 96% of the US population). 2 Analyses were weighted to account for the sampling design and generate nationally representative estimates. This analysis was deemed exempt from obtaining informed consent by the Weill Cornell Medicine institutional review board.…”

mentioning

confidence: 99%

“…A statistical brief suggested RBC transfusions may be declining in the United States, but this study excluded children and did not examine trends in plasma or platelet transfusion. 2 Preliminary data by the AABB (formerly the American Association of Blood Banks) and the US Centers for Disease Control and Prevention that focused on number of units of blood collected also suggested a decrease in the total number of RBC units transfused that may have begun as early as 2008. [4][5][6] However, in this study the percentage of hospitalized patients receiving RBC transfusions did not decrease until 2011.…”

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confidence: 99%

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Trends in Red Blood Cell, Plasma, and Platelet Transfusions in the United States, 1993-2014

Goel

Chappidi

Patel

et al. 2018

JAMA

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Blood transfusions are one of the most common hospital procedures. Randomized trials have demonstrated the safety of restrictive transfusion strategies. 1 Hospitals have subsequently implemented patient blood management programs to facilitate restrictive transfusion practices aimed to improve patient outcomes, reduce costs, and conserve blood. We are unaware of nationally representative studies evaluating temporal trends in red blood cell (RBC), plasma, and platelet transfusions while accounting for the influence of patient-level or hospitallevel characteristics.

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Section: Methodsmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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Trends in Red Blood Cell, Plasma, and Platelet Transfusions in the United States, 1993-2014

Goel

Chappidi

Patel

et al. 2018

JAMA

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“…The survival of red cells is reduced to 45-85 days, which is a significant decrease. 6 The absence of iron stores and erythroid hyperplasia is shown in the normocellular bone marrow and normal or decreased levels of serum iron, elevated total iron binding capacity (TIBC) and low transferrin saturation are manifested. Mainly, iron is stored in the body as ferritin, and a reduction in its level has an important role in making an investigation for iron deficiency.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Iron Deficiency in Children With Hypochromia and Microcytosis on Blood Smears

Muhammad Faisal,

Sajid Mustafa,

Muhammad Yasin

et al. 2023

Pak Postgrad Med J.

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Background: The relationship between iron deficiency and certain phenomenon like hematological alterations, inadequate growth, altered thermoregulatory function and reduced cognitive function have been well known. Objectives: To determine the frequency of iron deficiency in children with hypochromic and microcytic anemia on blood smears. Methods: This case-control study was performed in the department of pediatrics, Sahiwal Teaching Hospital, Sahiwal, Pakistan from May 2022 to April 2023. For cases, we included 179 children of both genders aged between 1 month and 15 years with hypochromia and microcytosis. Similar number of healthy children (n=179) of both gender and aged below 15 years were enrolled as controls. At the time of enrollment, socio-demographic information like gender, age and residential area were recorded. Local institutional laboratory was utilized for the hematological parameters. Hypochromia and microcytosis were labeled as MCV< 76fl and MCHC < 30 g/dl of red cells while blood film also depicted hypochromia and microcytosis. IDA was termed as serum ferritin < 12 ng/dl. Results In a total of 358 children, there were 192 (53.6%) boys. The mean age was 7.8±3.2 years while 184 (51.4%) children were between 6-15 years. Residential status of 196 (54.7%) children was rural. Overall, iron deficiency was diagnosed in 209 (58.4%) children. Among cases, 171 (95.5%) children had iron deficiency while among controls, 38 (21.2%) children had IDA (p<0.0001). Cases and controls were compared for various hematological laboratory parameters and statistically significant differences were observed for all parameters among cases and controls (p<0.0001). Conclusion: The frequency of iron deficiency was 95.5% among children with hypochromia and microcytosis on blood smears. Hematological parameters were significantly deranged among children with hypochromia and microcytosis when compared to healthy children.

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Red Blood Cell Transfusion

Cited by 2 publications

References 78 publications

Trends in Red Blood Cell, Plasma, and Platelet Transfusions in the United States, 1993-2014

Trends in Red Blood Cell, Plasma, and Platelet Transfusions in the United States, 1993-2014

Frequency of Iron Deficiency in Children With Hypochromia and Microcytosis on Blood Smears

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