Red cell distribution width is a predictor of mortality in patients with severe sepsis and septic shock

Balta, Şevket; Demırkol, Sait; Hatipoğlu, Mustafa; Ardıç, Şükrü; Arslan, Zekeriya; Çelik, Turgay

doi:10.1016/j.ajem.2013.02.031

Cited by 35 publications

(23 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thyroid dysfunction, nutritional deficiency, bone marrow dysfunction, and race are known to affect RDW levels. 10 All of the patients in our study were of the same race; in addition, they had no thyroid dysfunction, nutritional deficiency, or bone marrow dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Kayıpmaz

Findik²,

Kavalcı³

et al. 2017

Exp Clin Transplant

View full text Add to dashboard Cite

Objectives: Organ transplant is an effective treat ment for patients with end-stage renal and hepatic failure. Increased use has introduced more emergency department admissions of infectious origin after transplant. Because infections usually manifest with simple complaints and fever, emer gency physicians need laboratory tests and radiologic imaging procedures to quickly detect the presence and source of infection. Our aim was to analyze fever-related emergency admissions of renal and hepatic graft recipients and determine whether admitted patients had increased red blood cell distribution width and mean platelet volume levels. Materials and Methods:We reviewed the medical records of renal and hepatic graft patients who presented to our emergency department with fever during a 4-year period. Our analyses included 150 patients in which complete blood count and C-reactive protein results were available and the source of infection was determined. We compared results with a control group of 150 transplant patients without any infectious findings. Results: In the 150 solid-organ graft recipients who presented to our emergency department with fever, significant differences were observed versus control patients with respect to white blood cell count, neutrophil-to-lymphocyte ratio, red blood cell distribution width, mean platelet volume, and C-reactive protein levels (P < .05). We determined that C-reactive protein levels, red blood cell distribution width, mean platelet volume, and lymphocyte count were independent indicators of infection on multiple logistic regression analyses. We also determined that red blood cell distribution width had a specificity of 94% and a sensitivity of 26%. Conclusions: We found a significantly higher red blood cell distribution width in emergency admissions of infectious origin of renal and hepatic graft recipients than in the control group (P < .001), suggesting that this measurement is a suitable marker of infection for the emergency setting by virtue of rapid availability of test results and lack of extra costs.

show abstract

Section: Discussionmentioning

confidence: 99%

Untitled

Kayıpmaz

Findik²,

Kavalcı³

et al. 2017

Exp Clin Transplant

View full text Add to dashboard Cite

show abstract

“…RDW has recently been defined to highly correlate with short-and long-term outcomes in different clinical settings. However, RDW may also reflect ethnicity, neurohumoral activation, renal dysfunction, thyroid disease, hepatic dysfunction, nutritional deficiencies (ie, iron, vitamin B 12 , and folic acid), bone marrow dysfunction, inflammatory diseases, chronic or acute systemic inflammation, 9 and use of some medications or could represent an integrative measure of all these pathological processes occurring during the progression of CAD.…”

Section: To the Editormentioning

confidence: 99%

Response to Incremental Predictive Value of Red Cell Distribution Width for 12‐Month Clinical Outcome After Acute Myocardial Infarction

Demırkol

Balta

Küçük

et al. 2013

Clinical Cardiology

Self Cite

View full text Add to dashboard Cite

show abstract

“…4 However, RDW can reflect ethnicity, neurohumoral activation, renal dysfunction, thyroid disease, hepatic dysfunction, nutritional deficiencies (ie, iron, vitamin B 12 , and folic acid), bone marrow dysfunction, inflammatory diseases, chronic, or acute systemic inflammation. 5 Also, the value of RDW is instrument dependent forcing each laboratory to establish its own reference values.…”

mentioning

confidence: 99%