Red cell distribution width predicts mortality in infective endocarditis

Güray, Yeşım; İpek, Esra Gücük; Güray, Ümit; Demirkan, Burcu; Kafes, Habibe; Asarcıklı, Lale Dinç; Çabuk, Gizem; Yilmaz, Mehmet Birhan

doi:10.1016/j.acvd.2014.04.008

Cited by 24 publications

(22 citation statements)

References 34 publications

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“…The adjusted OR rose from1.12 to 1.40. RDW was reported as a binary variable in 2 studies [28, 33], and we found that the increased RDW levels were associated with a higher risk of death (OR, 2.12; 95%CI, 1.82–2.46) with low heterogeneity ( I 2 = 0, P = 0.49). And 4 studies provided data on AUC from 0.63 to 0.76 of RDW in prediction mortality [23, 25, 31, 33].…”

Section: Resultsmentioning

confidence: 84%

“…RDW was reported as a binary variable in 2 studies [28, 33], and we found that the increased RDW levels were associated with a higher risk of death (OR, 2.12; 95%CI, 1.82–2.46) with low heterogeneity ( I 2 = 0, P = 0.49). And 4 studies provided data on AUC from 0.63 to 0.76 of RDW in prediction mortality [23, 25, 31, 33]. Finally, three studies reported RDW as a categorical variable [25, 27, 29], and a rank correlation was found between the RDW levels and mortality in these patients.…”

Section: Resultsmentioning

confidence: 84%

“…A total of 32 observational studies met the pre-defined inclusion criteria and were included [1, 2, 9–11, 13–25, 27–29, 31–33, 36, 37]. The flow sheet of research selection was showed in Fig 1.…”

Section: Resultsmentioning

confidence: 99%

“…Among the 32 included studies, 6 studies belonged to the group A [1, 2, 9–11, 38], 9 studies belonged to the group B [23–25, 27–29, 31–33], and 17 studies belonged to the group C [13–22, 36, 37, 39–43]. As for the effect size, RDW was reported as a continuous variable (per 1% increase) in 16 studies [1, 9–11, 16, 17, 21–23, 29, 31, 32, 36, 37, 40, 43], as a binary variable in 8 studies [14, 16, 18, 19, 26, 33, 36, 40], and as a categorical variable in 8 studies [2, 13, 17, 22, 25, 27, 29, 42]. The AUC of RDW for mortality prediction was reported in 25 studies.…”

Section: Resultsmentioning

confidence: 99%

“…RDW is cost-effective and is routinely reported in the complete blood count (CBC) [9–18]. A growing body of evidence indicates the importance of RDW in predicting mortality rate in critically or acutely ill patients [19–33]. Nevertheless, the value of RDW has often been neglected by almost all clinicians in non-cardiovascular conditions.…”

Section: Introductionmentioning

confidence: 99%

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Prognostic Value of Red Blood Cell Distribution Width in Non-Cardiovascular Critically or Acutely Patients: A Systematic Review

Luo

Jiang

et al. 2016

PLoS ONE

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BackgroundRDW (red cell distribution width) has been reported to been associated with the prognosis of patients with cardiovascular diseases. However, RDW is often overlooked by clinicians in treating patients with non-cardiovascular diseases, especially in an emergency. The objective of this systematic review is to explore the prognostic value of RDW in non-cardiovascular emergencies.MethodsPubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were systematically searched from their inception to December 31, 2015. We included studies examining the relationship between RDW and mortality rate by adjusting important covariables in non-cardiovascular emergencies. All included studies were divided into three groups. Group A: general critically ill patients; Group B: patients with infectious disease; Group C: other conditions. We extracted each study’ characteristics, outcomes, covariables, and other items independently.ResultsA total of 32 studies were eligible for inclusion in our meta-analysis. Six studies belonged to Group A, 9 studies belonged to Group B and 17 studies belonged to Group C. Among these included studies, RDW was assessed as a continuous variable (per 1% increase) in 16 studies, as a binary variable in 8 studies, and as a categorical variable in 8 studies. In addition, AUCs (area under the receiver operating characteristic curve) of RDW for predicting mortality were reported in 25 studies. All studies were published between 2011–2015. The qualities of included 32 studies were moderate or high.ConclusionThe present systematic review indicates that the increased RDW is significantly associated with a higher mortality rate in an non-cardiovascular emergency. The low cost and readily accessible of this laboratory variable may strengthen its usefulness in daily practice in the future.

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Section: Resultsmentioning

confidence: 84%

Section: Resultsmentioning

confidence: 84%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Prognostic Value of Red Blood Cell Distribution Width in Non-Cardiovascular Critically or Acutely Patients: A Systematic Review

Luo

Jiang

et al. 2016

PLoS ONE

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Bartonella henselae mitral valve endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia in a cat

Colella,

Greco,

Cordisco

et al. 2023

Vet Record Case Reports

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Feline infective endocarditis is a difficult condition to detect and diagnose early, with a poor long‐term prognosis. This case report describes the clinical, laboratory, instrumental and histological findings in a 12‐year‐old cat with Bartonella henselae endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia. The latter pathogen recently emerged as deadly nosocomial bacteria in humans and is considered a common cause of infective endocarditis. The prolonged corticosteroid therapy administered in the cat probably played a role in the onset of B. henselae endocarditis and E. faecalis intestinal translocation and bacteraemia. Echocardiography remains the tool of choice to suspect infective endocarditis, as it can detect vegetative lesions consistent with this condition. Feline infective endocarditis should always be considered as a differential diagnosis in cats, especially when there are signs of systemic disease, a history of prolonged corticosteroid treatment or concomitant infections.

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Toward a Blood-Borne Biomarker of Chronic Hypoxemia: Red Cell Distribution Width and Respiratory Disease

Ycas¹

2017

Advances in Clinical Chemistry

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Red cell distribution width predicts mortality in infective endocarditis

Abstract: According to our results, mortality is high in patients with IE. RDW is a promising biomarker for predicting 1-year survival rates in these patients.

Cited by 24 publications

References 34 publications

Prognostic Value of Red Blood Cell Distribution Width in Non-Cardiovascular Critically or Acutely Patients: A Systematic Review

Prognostic Value of Red Blood Cell Distribution Width in Non-Cardiovascular Critically or Acutely Patients: A Systematic Review

Bartonella henselae mitral valve endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia in a cat

Toward a Blood-Borne Biomarker of Chronic Hypoxemia: Red Cell Distribution Width and Respiratory Disease

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