Red cell distribution Width (RDW) and Increased Risk of Recurrent Acute Coronary Syndrome

Zorlu, Ali; Yücel, Hasan; Kaya, Hakki; Korkmaz, Özge Polat; Yıldırımlı, Kutay; Bektaşoğlu, Gökhan

doi:10.15824/actamedica.06292

Cited by 6 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Table 1 [ 17 - 29 ] summarizes the details of the included studies. These studies were published from 2010 to 2016, with population sizes ranging from 100 to 2,506.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Red Cell Distribution Width and Mortality in Patients With Acute Coronary Syndrome: A Meta-Analysis on Prognosis

et al. 2018

View full text Add to dashboard Cite

BackgroundRed cell distribution width (RDW), a routine component of the complete blood count (CBC), measures variation in the size of circulating erythrocytes. It has been associated with several clinical outcomes in cardiovascular disease. We sought to strengthen the association between RDW and mortality in patients admitted for acute coronary syndrome (ACS) by pooling together data from available studies.MethodsStudies that fulfilled the following were identified for analysis: 1) observational; 2) included patients admitted for ACS; 3) reported data on all-cause or cardiovascular (CV) mortality in association with a low or high RDW; and 4) used logistic regression analysis to control for confounders. Using MEDLINE, Clinical Key, ScienceDirect, Scopus, and Cochrane Central Register of Controlled Trials databases, a search for eligible studies was conducted until January 9, 2017. The quality of each study was evaluated using the Newcastle-Ottawa Quality Assessment Scale. Our primary outcome of interest was all-cause or CV mortality. We also investigated the impact of RDW on major adverse cardiovascular events (MACEs) for the studies that reported these outcomes. Review Manager (RevMan) 5.3 was utilized to perform Mantel-Haenzel analysis of random effects and compute for relative risk.ResultsWe identified 13 trials involving 10,410 patients, showing that in ACS, a low RDW is associated with a statistically significant lower all-cause or CV mortality (RR 0.35, (95% CI 0.30 to 0.40), P < 0.00001, I2 = 53%), a finding that was consistent both in the short- and long-term.ConclusionsA low RDW is also associated with lower risk for MACEs after an ACS (RR 0.56, (95% CI 0.51 to 0.61), P < 0.00001, I2 = 91%). A low RDW during an ACS is associated with lower all-cause or CV mortality and lower risk of subsequent MACEs, providing us with a convenient and inexpensive risk stratification tool in ACS patients.

show abstract

“…Table 1 [ 17 - 29 ] summarizes the details of the included studies. These studies were published from 2010 to 2016, with population sizes ranging from 100 to 2,506.…”

Section: Resultsmentioning

confidence: 99%

“…For quality assessment, six of the included studies were given the highest rating of nine stars on the Newcastle-Ottawa Scale, with the rest of the studies receiving seven to eight stars ( Table 2 [ 17 - 29 ]). The study by Cavusoglu et al [ 19 ] had a submaximal score for cohort selection because it only included male patients.…”

Section: Resultsmentioning

confidence: 99%

Red Cell Distribution Width and Mortality in Patients With Acute Coronary Syndrome: A Meta-Analysis on Prognosis

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Hematological parameters including hemoglobin level, leukocyte, neutrophil and lymphocyte counts, Mean Platelet Volume (MPV) and ratios including Neutrophil/Lymphocyte Ratio, Red Cell Distribution Width (RDW), Platelet Distribution Width (PDW) are demonstrating measure of the general inflammatory activity which provides prognostic information related to some ischemic disorders (4)(5)(6). It gives also economic and fast information about inflammation that is responsible for the pathogenesis of cardiovascular disease.…”

Section: Introductionmentioning

confidence: 99%

The Red Cell Distribution Width is Strong Predictor for the in-Hospital Mortality of the CABG Patients

Katlandur¹,

Özdil²,

Özbek³

et al. 2016

Acta Med Anatol

View full text Add to dashboard Cite

Introduction:There are several studies about the mortality of the CABG patients with the importance of the inflammation. The aim of our study was to evaluate the relationship between RDW and in-hospital mortality in CABG patients.Methods: A total of 346 patients undergoing coronary artery bypass grafting operation were analyzed for our study. Preoperative 2 ml blood sample was put into tubes for evaluation all patients complete blood count. All patients underwent same anesthesia protocol. The type of CABG procedure (off-pump vs on-pump CABG) was determined by the operation team. Results:There was ten patients died in-hospital period (Group 1) and three hundred and thirty-six patients lived during in hospital follow up (Group 2). WBC (10.8 ± 5.2 x 103 vs 7.9 ± 2.2 x 103 p: 0.04), Neutrophil (7.3 ± 3 x 103 vs 5.1 ± 2 x 103 p: 0.03), N/L Ratio (4.8 ± 2.6 % vs 2.7 ± 1.6 % p: 0.01) and RDW (14.8 ± 1.6 % vs 13.9 ± 6.6 %, p: 0.002) values were higher in group 1 than group 2, respectively. A logistic multivariate regression analysis showed that only RDW (OR 1.860, 95% CI 1.105-3.132; p: 0.02) was an independent predictor of the development of mortality in-hospital period in CABG patients. Conclusion:To our knowledge, this is the first report of an association between RDW and the development postoperative mortality in CABG patients. Keywords:Red cell distribution width, In-Hospital mortality, Coronary artery bypass grafting. Received: 02.03.2016 Accepted: 08.04.2016 doi: 10.5505/actamedica.2016 AbstractThe Red Cell Distribution Width is Strong Predictor for the in-Hospital Mortality of the CABG Patients

show abstract

“…et al, 2018, 1 (2),[19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] For each patient, a detailed history, complete physical examination 12-lead ECG, and routine laboratory including serum cardiac markers were performed . Wall motion abnormalities The LV was divided according to the 16-segment model as proposed by ASE For each segments, wall motion was identified.…”

mentioning

confidence: 99%

Relation between Red Blood Cell Distribution Width and Left Ventricular Function In Acute Coronary Syndrome Patients

Elkhashab

Elshafie

Razek

et al. 2018

Fayoum University Medical Journal

View full text Add to dashboard Cite

show abstract

Red cell distribution Width (RDW) and Increased Risk of Recurrent Acute Coronary Syndrome

Cited by 6 publications

References 0 publications

Red Cell Distribution Width and Mortality in Patients With Acute Coronary Syndrome: A Meta-Analysis on Prognosis

Red Cell Distribution Width and Mortality in Patients With Acute Coronary Syndrome: A Meta-Analysis on Prognosis

The Red Cell Distribution Width is Strong Predictor for the in-Hospital Mortality of the CABG Patients

Relation between Red Blood Cell Distribution Width and Left Ventricular Function In Acute Coronary Syndrome Patients

Contact Info

Product

Resources

About