Red cell distribution width (RDW) in the diagnosis of iron deficiency with microcytic hypochromic anemia

Abstract

RDW has a limited specificity for diagnosis of IDA among children with microcytic hypochromic anemia.

Evaluation of red cell distribution width in the diagnosis of iron deficiency anemia

“…Small red blood cells known as microcytes, with MCV <80 fl can arise from iron deficiency, chronic diseases, hemoglobinopathies, lead poisoning. [4][5][6] Iron deficiency anemia is the most prevalent microcytic hypochromic anemia worldwide including India. 6,7 All women of reproductive age group, pregnant females, infants, young children, adolescents and elderly are at a higher risk of nutritional anemias in developing nations because of increased demand and or low intake.…”

“…[4][5][6] Iron deficiency anemia is the most prevalent microcytic hypochromic anemia worldwide including India. 6,7 All women of reproductive age group, pregnant females, infants, young children, adolescents and elderly are at a higher risk of nutritional anemias in developing nations because of increased demand and or low intake. 1,8,9 It, therefore, becomes necessary to point to a definitive diagnosis of microcytic anemias to differentiate iron deficiency anemias from other causes since pathogenesis, prognosis and treatment is different for every cause.…”

“…1,8,9 It, therefore, becomes necessary to point to a definitive diagnosis of microcytic anemias to differentiate iron deficiency anemias from other causes since pathogenesis, prognosis and treatment is different for every cause. 5,6 Complete blood counts including red blood cell (RBC) parameters evaluated with the help of automated hematology analyzers form an integral part of routine hematological work up and thus are the backbone for elucidating the diagnosis of anemias. 3 The RBC parameters gives an effective quantitative assessment of red blood cells.…”

“…RDW, alongside other red cell indices, can be cost effective in early diagnosis of iron deficiency anemia with sufficient accuracy and minimal testing. 6,7 The present study was undertaken to evaluate RDW as a screening test for diagnosis of iron deficiency anemia.…”

Mean platelet volume/platelet count ratio in anemia

“…To the Editor, Iron deficiency anemia (IDA) is the most prevalent micronutrient deficiency in the world, and the leading cause of anemia [1,2]. IDA is due to a defect in hemoglobin (Hb) synthesis that results in microcytic red blood cells (RBC) and decreased amount of Hb [3].…”