Red fluorescent ZnO nanoparticle grafted with polyglycerol and conjugated RGD peptide as drug delivery vehicles for efficient target cancer therapy

Yang, Xiaoxin; Zhang, Chuang; Li, Anxia; Wang, Jie; Cai, Xiulan

doi:10.1016/j.msec.2018.10.066

Cited by 58 publications

(24 citation statements)

References 47 publications

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“…In comparison to other oxide semiconductors, ZnO has many superior properties such as light sensitive, thermal and chemically stable, low cost, nontoxic, and sustainable with hydrogen environment [3]. The ZnO-based materials have many applications in industries, for example, rubbers, ceramics, pharmaceuticals, agricultural servants, paints, cosmetics, and photocatalysts [4][5][6][7][8][9][10]. Besides the advantages of this material due to the high electron aperture rate and low charge separation efficiency [11], the pure ZnO often exhibits relatively low photocatalytic activity under visible light irradiation, and therefore, ZnO does not meet the requirements of a photocatalyst when applied to practical processes [3,12,13].…”

Section: Introductionmentioning

confidence: 99%

Facile Preparation of ZnO Nanoparticles and Ag/ZnO Nanocomposite and Their Photocatalytic Activities under Visible Light

Pham

Tran

et al. 2020

International Journal of Photoenergy

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Zinc oxide (ZnO) has been known as an excellent photocatalyst for the degradation of a variety of organic pollutants under UV irradiation. This work describes a synthesis of ZnO nanoparticles via a facile precipitation method, and Ag was doped into Ag/ZnO nanocomposite to improve the photocatalytic degradation of BPA under visible light irradiation. The obtained ZnO nanoparticles were 20 nm in size and had a relatively high surface area and pore volume, 26.2 m2/g and 0.48 cm3/g, respectively. The deposition of Ag led to a decrease in the surface area, pore volume, and band gap energy ( E g ) of ZnO nanoparticles. However, the photocatalytic activity of Ag/ZnO composite in the case increased. The performance of ZnO was compared with Ag/ZnO composites at the different molar ratios, and the kinetic reaction of BPA in these catalysts was investigated by the first-order kinetic model. The sample of Ag/ZnO-10 composite had the highest catalytic activity and showed the degradation efficiency, reaction rate, and degradation capacity of 100% in 120 min, 0.014 min-1, and 40 mg/g, respectively. In comparison, the effects of Ag/ZnO molar ratio, catalyst dosage, solution pH, and concentration of BPA on photocatalytic degradation were investigated. Additionally, the photocatalytic performance of Ag/ZnO-10 composite was evaluated by the degradation of other persistent organic compounds such as phenol, tartrazine, and methylene blue and compared to other catalysts in literature.

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Section: Introductionmentioning

confidence: 99%

Facile Preparation of ZnO Nanoparticles and Ag/ZnO Nanocomposite and Their Photocatalytic Activities under Visible Light

Pham

Tran

et al. 2020

International Journal of Photoenergy

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“…This result is consistent with a number of literature reports on the difference in RGD peptide labeling effects between U87MG and HeLa cells. [45][46][47][48][49] This experiment demonstrates the abilities of the supraparticle coassemblies for bioconjugation, biological labeling, and biological imaging. Second, hydrophobic SPIONs and QDs were mixed with BSA to form SPION and QD co-encapsulated assemblies, i.e., SPIONs&QDs@BSA.…”

Section: Resultsmentioning

confidence: 99%

Spontaneous and instant formation of highly stable protein–nanoparticle supraparticle co-assemblies driven by hydrophobic interaction

Liu

Ding

et al. 2019

Nanoscale Adv.

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“…More recently, Yang et al. synthesized red fluorescence ZnO NPs with grafted polyglycerol (PG) layer through ring‐opening polymerization of glycidol, [ 161 ] followed by these ZnO‐PG NPs were engineered by conjugating with arginine‐glycine‐aspartate (RGD) peptide via stepwise organic reactions ( Figure a). The as‐prepared ZnO‐PG‐RGD NPs were employed as drug carriers for loading and releasing anticancer drugs Doxorubicin hydrochloride (DOX).…”

Section: Biomedical Applications Of Peptide‐engineered Fluorescent Namentioning

confidence: 99%

Peptide‐Engineered Fluorescent Nanomaterials: Structure Design, Function Tailoring, and Biomedical Applications

Wang

Xia

Wang

et al. 2021

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Fluorescent nanomaterials have exhibited promising applications in biomedical and tissue engineering fields. To improve the properties and expand bioapplications of fluorescent nanomaterials, various functionalization and biomodification strategies have been utilized to engineer the structure and function of fluorescent nanomaterials. Due to their high biocompatibility, satisfied bioactivity, unique biomimetic function, easy structural tailoring, and controlled self‐assembly ability, supramolecular peptides are widely used as versatile modification agents and nanoscale building blocks for engineering fluorescent nanomaterials. In this work, recent advance in the synthesis, structure, function, and biomedical applications of peptide‐engineered fluorescent nanomaterials is presented. Firstly, the types of different fluorescent nanomaterials are introduced. Then, potential strategies for the preparation of peptide‐engineered fluorescent nanomaterials via templated synthesis, bioinspired conjugation, and peptide assembly‐assisted synthesis are discussed. After that, the unique structure and functions through the peptide conjugation with fluorescent nanomaterials are demonstrated. Finally, the biomedical applications of peptide‐engineered fluorescent nanomaterials in bioimaging, disease diagnostics and therapy, drug delivery, tissue engineering, antimicrobial test, and biosensing are presented and discussed in detail. It is helpful for readers to understand the peptide‐based conjugation and bioinspired synthesis of fluorescent nanomaterials, and to design and synthesize novel hybrid bionanomaterials with special structures and improved functions for advanced applications.

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Red fluorescent ZnO nanoparticle grafted with polyglycerol and conjugated RGD peptide as drug delivery vehicles for efficient target cancer therapy

Cited by 58 publications

References 47 publications

Facile Preparation of ZnO Nanoparticles and Ag/ZnO Nanocomposite and Their Photocatalytic Activities under Visible Light

Facile Preparation of ZnO Nanoparticles and Ag/ZnO Nanocomposite and Their Photocatalytic Activities under Visible Light

Spontaneous and instant formation of highly stable protein–nanoparticle supraparticle co-assemblies driven by hydrophobic interaction

Peptide‐Engineered Fluorescent Nanomaterials: Structure Design, Function Tailoring, and Biomedical Applications

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