2012
DOI: 10.1007/s00247-011-2330-x
|View full text |Cite
|
Sign up to set email alerts
|

Red nucleus degeneration in hypertrophic olivary degeneration after pediatric posterior fossa tumor resection: use of susceptibility-weighted imaging (SWI)

Abstract: We report the use of susceptibility-weighted imaging (SWI) in detection of red nucleus (rubral) degeneration and atrophy in children with hypertrophic olivary degeneration (HOD) after posterior fossa tumor resection. The use of this modality for this particular application has not been previously described. Detection of red nucleus changes seems to be facilitated by the contrast mechanism of SWI over conventional MRI sequences. SWI can be considered in the evaluation of these patients and in the future might p… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
13
0

Year Published

2013
2013
2024
2024

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 18 publications
(13 citation statements)
references
References 7 publications
0
13
0
Order By: Relevance
“…26 In addition, susceptibility-weighted imaging has been utilized to study the red nucleus degeneration and atrophy in children with HOD after posterior fossa tumour resection. 27 This indicates that quantitative imaging studies may better define the extent of the lesions in these patients and may be a future area of research.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…26 In addition, susceptibility-weighted imaging has been utilized to study the red nucleus degeneration and atrophy in children with HOD after posterior fossa tumour resection. 27 This indicates that quantitative imaging studies may better define the extent of the lesions in these patients and may be a future area of research.…”
Section: Discussionmentioning
confidence: 99%
“…20 In addition, the reports on hypertrophic olivary degeneration in paediatric patients are limited. 15,[25][26][27] In this report, we sought to analyse whether bilateral symmetrical inferior olivary nucleus hypertrophy is specifically associated with mitochondrial disorders in children.…”
Section: Resultsmentioning
confidence: 99%
“…7 In children, disruptive lesions of the GMT may include low-and high-grade tumors and vascular malformations. 10,12,14,16,21 Neurophysiologically, this causes the removal of inhibition of the electrotonic gap junctions in the inferior olivary nucleus. 3,18 On histopathology, disinhibition and deafferentation of the inferior olivary nucleus result in vacuolar degeneration and enlargement of neurons and an increase in glial cells and hypertrophy of astrocytes.…”
Section: Discussionmentioning
confidence: 99%
“…102 The potential advantages of SWI in DBS and Gamma Knife radiosurgery, among other procedures, have led to a significant number of studies further examining the role of SWI in applications for functional neurosurgery. 1,14,22,39,43,44,55,66,74,80,91,103,106,116 Fig. 10.…”
Section: Swi In Functional Neurosurgerymentioning
confidence: 99%
“…96 Complications can arise when coordinates obtained from MR images and atlas mapping do not correspond, leading to malpositioning of electrodes. 85 SWI can be used to clearly visualize the red nucleus, 103 substantia nigra (SN), globus pallidus (GP), subthalamic nucleus (STN), 1 along with various brainstem nuclei, such as the inferior olive and spinal trigeminal nucleus 22 (based on differential iron deposition), which can assist in presurgical planning and diagnostic purposes. The ability of SWI to depict the venous network around the brainstem will provide neurosurgeons with even more information to plan surgical approaches in the infratentorial regions, as well as decide the final placement of electrodes, which can help prevent intracerebral hemorrhage.…”
Section: Deep Brain Stimulationmentioning
confidence: 99%