‘Red Ruby’: an interactive web-based intervention for lifestyle modification on metabolic syndrome: a study protocol for a randomized controlled trial

Jahangiry, Leila; Shojaeizadeh, Davoud; Najafi, Moslem; Mohammad, Kazem; Farhangi, Mahdieh Abbasalizad; Montazeri, Ali

doi:10.1186/1471-2458-14-748

Cited by 21 publications

(13 citation statements)

References 77 publications

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“…This study was a cross-sectional investigation of 160 Iranian adults patients with metabolic syndrome living in Tehran; the details of this study has been reported elsewhere [11,12]. Briefly this was an internet-based life style modification interactive program, and we enrolled community-dwelling individuals from Jun 22 to August 22, 2012.…”

Section: Methodsmentioning

confidence: 99%

Association between dietary patterns and metabolic syndrome in a sample of Tehranian adults

Farhangi

Jahangiry

Jafarabadi

et al. 2016

Obesity Research & Clinical Practice

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Section: Methodsmentioning

confidence: 99%

Association between dietary patterns and metabolic syndrome in a sample of Tehranian adults

Farhangi

Jahangiry

Jafarabadi

et al. 2016

Obesity Research & Clinical Practice

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“…Details of the study design have been submitted elsewhere. [ 33 34 ] Participants were recruited from an online registration website namely Healthy Heart Education ( http://www.Heartresearch.ir ). This website is designed to increase public's awareness about CVDs and MetS.…”

Section: Methodsmentioning

confidence: 99%

Health-related quality of life among people participating in a metabolic syndrome e-screening program: A web-based study

et al. 2016

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Background:Cardiovascular diseases remain the leading cause of death worldwide. Metabolic syndrome (MetS) is the clustering of risk factors for developing the disease. Strong evidence exists for the efficacy of screening for MetS. However, the potential of novel web-based studies for MetS and online assessing of the quality of life (QOL) for these high-risk participants have not been explored.Methods:This was a web-based, cross-sectional study. Participants were recruited through online registering on the study website. Then, those who met the study criteria (waist circumference [WC] ≥90 and blood pressure [BP] ≥130/85) were contacted and invited for the clinical assessments, if they wish. Baseline measurements were MetS risk factors (weight, WC, body mass index and BP, total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, triglycerides, and fasting blood glucose) and health-related QOL (HRQOL) that was measured using the short form-36 (SF-36).Results:There were 1436 (male: 928, female: 508) registration data on the study website. Reviewing the data, of 317 eligible participants that were invited to the study, 229 persons were responded to invitation in the screening program. The mean age of participants was 43.8 (standard deviation [SD] = 9.9) years. MetS was more frequent in male and married persons. In addition, participants with MetS had lower mean (SD) scores than participants without MetS for the following subscales of HRQOL as: role-physical (with MetS 51.1±35.2; versus without MetS 65.3 ± SD = 40.1), vitality (with MetS 65± 21; versus without MetS 75.3 ± 21.1), mental health (with MetS 49.5±30.1; versus without MetS 34.1±17.2)(P < 0.05 for all).Conclusions:People with MetS experienced lower HRQOL than without MetS. Internet as a powerful medium offers a novel setting for delivery health information. It seems that high BP and abdominal obesity are associated with lower HRQOL in the participants with MetS. A web-based prevention program could make people aware for their vulnerability to MetS and its complications.

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“…The Red Ruby was a randomized controlled trial conducted in Tehran, Iran. A detailed description of the method can be found elsewhere in a presentation of the study protocol [ 19 ]. Briefly, this study was designed to assess the effects of interactive web-based lifestyle intervention on metabolic syndrome.…”

Section: Methodsmentioning

confidence: 99%

Interactive web-based lifestyle intervention and metabolic syndrome: findings from the Red Ruby (a randomized controlled trial)

Jahangiry

Shojaeizadeh

Farhangi

et al. 2015

Trials

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BackgroundMetabolic syndrome is a growing public health problem worldwide. Several interventions have been proposed to specifically target the problem. This study evaluated the effectiveness of an interactive web-based lifestyle for management of metabolic syndrome.MethodsThis randomized controlled trial was conducted from June through August 2012 in Tehran, Iran. Participants were individuals with metabolic syndrome who had registered on the study website. Interested eligible participants were invited for a free clinic visit and clinical assessment. They were randomly assigned to the intervention (n = 80) or control (n = 80) group. The intervention group received an interactive web-based program called the Healthy Heart Profile and were followed for 6 months. The control group received general information on metabolic syndrome. Anthropometric measures, glycemic status, and lipid profile were evaluated at baseline, and at 3- and 6-month follow-up assessments. Metabolic syndrome was defined according to The National Cholesterol Education Program Adult Treatment Panel (ATP) III report except for waist circumference, which was modified to ≥90 cm for both genders for the Iranian population.ResultsIn total, 1,437 individuals registered on the study website. The mean age of participants was 44.2 years (SD = 10.0). There were no significant differences between the intervention and control groups on any baseline variable except that participants in the intervention group recorded higher levels of LDL. The results showed a decrease in metabolic syndrome in both groups. These reductions were significantly greater in the intervention group at the 3- and 6-month follow-ups. The intervention group showed significantly greater decreases (P < 0.05) over the control group for, respectively, systolic blood pressure (3-month: −10 versus −6 mmHg; 6-month: −11 versus −8 mmHg), diastolic blood pressure (3-month: −10 versus −4 mmHg; 6-month: −11 versus −6 mmHg), weight (3-month: −2 versus −1 kg; 6-month: −4 versus −1 kg), body mass index (3-month: −0.5 versus −0.2 kg/m2; 6-month: −1.1 versus −0.4 kg/m2) and improvement in HDL (3-month: 2 versus 0.64 mg/dl; 6-month: 6 versus 4 mg/dl).ConclusionThe findings suggest that the web-based interactive program was beneficial for individuals with metabolic syndrome. Comprehensive interactive web-based prevention programs are promising to help involve patients in improving management of metabolic syndrome and adopting a healthy lifestyle.Trial registrationIRCT201111198132N1. Registered 27 May 2013.Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-015-0950-4) contains supplementary material, which is available to authorized users.

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‘Red Ruby’: an interactive web-based intervention for lifestyle modification on metabolic syndrome: a study protocol for a randomized controlled trial

Cited by 21 publications

References 77 publications

Association between dietary patterns and metabolic syndrome in a sample of Tehranian adults

Association between dietary patterns and metabolic syndrome in a sample of Tehranian adults

Health-related quality of life among people participating in a metabolic syndrome e-screening program: A web-based study

Interactive web-based lifestyle intervention and metabolic syndrome: findings from the Red Ruby (a randomized controlled trial)

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