“…These closures and related Markovianized versions such as the eddy-damped quasi-normal Markovian model (EDQNM, Orszag (1970) [54], Leith (1971) [55], Bowman, Krommes & Ottaviani (1993) [56], Frederiksen & Davies (1997) [57]), test field model (TFM, [58], [59], Leith & Kraichnan (1972) [60]) and realizable TFM (Bowman & Krommes (1997) [61]) have been successfully applied to a variety of important problems. Their performance has been compared with direct numerical simulations and experimental data (e.g., Herring et al (1974) [62], Pouquet et al (1975) [63], Kraichnan & Herring (1978) [64], McComb (1990) [65], McComb et al (1992) [46], Frederiksen, Davies & Bell (1994) [52], Frederiksen & Davies (2000, 2004 [66,67]). Importantly turbulence closures allow the study of the statistics of the predictability of homogeneous turbulent flows (Kraichnan (1970) [68], Leith (1971Leith ( , 1974 [55,69], Leith & Kraichnan (1972) [60], Métais & Lesieur (1986) [70]) and most recently of inhomogeneous turbulen...…”