“…The development of tubulo-interstitial syndrome on the 30 th day of the polyuric stage of sublimate nephropathy with hyposodium diet was characterized by an increase in crystalline substance [15][16][17][18][19][20][21][22][23] in the kidneys with a decrease in amorphous substance, with the most significant changes in renal medulla, in second place in the cortex and in third place in the papilla (Fig. 1).…”